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David L Steffen

Explore the profile of David L Steffen including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 191
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Recent Articles
1.
Ochsner S, Watkins C, McOwiti A, Xu X, Darlington Y, Dehart M, et al.
Physiol Genomics . 2012 Jul; 44(17):853-63. PMID: 22786849
The nuclear receptor (NR) superfamily of ligand-regulated transcription factors directs ligand- and tissue-specific transcriptomes in myriad developmental, metabolic, immunological, and reproductive processes. The NR signaling field has generated a wealth...
2.
McKenna N, Howard C, Aufiero M, Easton-Marks J, Steffen D, Becnel L, et al.
Mol Endocrinol . 2012 Jun; 26(10):1675-81. PMID: 22734043
The National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) supports multiple basic science consortia that generate high-content datasets, reagent resources, and methodologies, in the fields of kidney, urology, hematology,...
3.
Ochsner S, Watkins C, LaGrone B, Steffen D, McKenna N
Mol Endocrinol . 2010 Aug; 24(10):2065-9. PMID: 20685849
Nuclear receptors (NRs) are ligand-regulated transcription factors that recruit coregulators and other transcription factors to gene promoters to effect regulation of tissue-specific transcriptomes. The prodigious rate at which the NR...
4.
McKenna N, Cooney A, DeMayo F, Downes M, Glass C, Lanz R, et al.
Mol Endocrinol . 2009 May; 23(6):740-6. PMID: 19423650
Nuclear receptors and coregulators are multifaceted players in normal metabolic and homeostatic processes in addition to a variety of disease states including cancer, inflammation, diabetes, obesity, and atherosclerosis. Over the...
5.
Ochsner S, Steffen D, Hilsenbeck S, Chen E, Watkins C, McKenna N
Cancer Res . 2009 Jan; 69(1):23-6. PMID: 19117983
With large amounts of public expression microrray data being generated by multiple laboratories, it is a significant task for the bench researcher to routinely identify available datasets, and then to...
6.
Ochsner S, Steffen D, Stoeckert Jr C, McKenna N
Nat Methods . 2008 Nov; 5(12):991. PMID: 19034265
No abstract available.
7.
Gu P, Reid J, Gao X, Shaw C, Creighton C, Tran P, et al.
PLoS One . 2008 Jul; 3(7):e2548. PMID: 18648548
Background: MicroRNAS (miRNAS: a class of short non-coding RNAs) are emerging as important agents of post transcriptional gene regulation and integral components of gene networks. MiRNAs have been strongly linked...
8.
Lanz R, Jericevic Z, Zuercher W, Watkins C, Steffen D, Margolis R, et al.
Nucleic Acids Res . 2005 Dec; 34(Database issue):D221-6. PMID: 16381851
The nuclear receptor signaling (NRS) field has generated a substantial body of information on nuclear receptors, their ligands and coregulators, with the ultimate goal of constructing coherent models of the...