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David L Bigam

Explore the profile of David L Bigam including associated specialties, affiliations and a list of published articles. Areas
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Articles 106
Citations 1374
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Recent Articles
1.
Hefler J, Pawlick R, Marfil-Garza B, Thiesen A, Cuesta-Gomez N, Hatami S, et al.
Liver Res . 2025 Feb; 8(1):46-53. PMID: 39959032
Background And Aim: The liver is susceptible to ischemia-reperfusion injury (IRI) during hepatic surgery, when the vessels are compressed to control bleeding, or liver transplantation, when there is an obligate...
2.
Rouhi A, Verhoeff K, Anderson B, Dajani K, Bigam D, Shapiro A
Pancreatology . 2024 Dec; 25(1):147-152. PMID: 39694760
Background: Total pancreatectomy (TP) offers a surgical option for refractory pancreatitis, yet confers substantial long-term morbidity associated with resultant diabetes. While total pancreatectomy with islet autotransplantation (TPIAT) offers an intuitive...
3.
Jatana S, Krys D, Verhoeff K, Kung J, Jogiat U, Montano-Loza A, et al.
Transplantation . 2024 Dec; PMID: 39658843
Background: Recurrent disease after liver transplant is well recognized for many diseases. Metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MASH) are leading indications for liver transplant, and there is...
4.
Sawchuk T, Verhoeff K, Jogiat U, Mocanu V, Shapiro A, Anderson B, et al.
Surg Endosc . 2024 Jul; 38(9):5030-5040. PMID: 39009724
Background: Efforts to preoperatively risk stratify and optimize patients before pancreaticoduodenectomy continue to improve outcomes. This study aims to determine the impact of hypoalbuminemia on outcomes following pancreaticoduodenectomy and outline...
5.
Parente A, Verhoeff K, Kin T, Hefler J, Marfil-Garza B, Sanchez-Fernandez N, et al.
Transplant Direct . 2024 Jun; 10(7):e1667. PMID: 38911274
Background: Limited information is available regarding outcomes of islet cell isolation (ICI) and transplantation (ITx) using medical assistance in dying (MAiD) donors. We aimed to assess the feasibility and outcomes...
6.
Kirkland M, Verhoeff K, Jogiat U, Mocanu V, Shapiro A, Anderson B, et al.
Surg Endosc . 2024 Jun; 38(8):4287-4295. PMID: 38872019
Background: Biliary obstruction before liver resection is a known risk factor for post-operative complications. The aim of this study was to determine the impact of persistent hyperbilirubinemia following preoperative biliary...
7.
Li W, van der Doef H, Wildhaber B, Marra P, Bravi M, Pinelli D, et al.
BMJ Open . 2024 Jun; 14(6):e081933. PMID: 38866577
Introduction: Hepatic artery complications (HACs), such as a thrombosis or stenosis, are serious causes of morbidity and mortality after paediatric liver transplantation (LT). This study will investigate the incidence, current...
8.
Hefler J, Hatami S, Thiesen A, Wagner M, Mainardi G, Himmat S, et al.
Ann Transplant . 2024 Jan; 29:e941054. PMID: 38287661
BACKGROUND Ischemia/reperfusion injury (IRI) is an inherent problem in organ transplantation, owing to the obligate period of ischemia that organs must endure. Cyclosporine A (CsA), though better know as an...
9.
Hefler J, Leon-Izquierdo D, Marfil-Garza B, Meeberg G, Verhoeff K, Anderson B, et al.
Am J Transplant . 2023 Apr; 23(7):976-986. PMID: 37086951
Normothermic machine perfusion (NMP) has emerged as a valuable tool in the preservation of liver allografts before transplantation. Randomized trials have shown that replacing static cold storage (SCS) with NMP...
10.
Verhoeff K, Webb A, Krys D, Anderson D, Bigam D, Fung C
J Can Assoc Gastroenterol . 2023 Apr; 6(2):86-93. PMID: 37025512
Background: Pancreatic cystic lesions (PCLs) are common, with several guidelines providing surveillance recommendations. The Canadian Association of Radiologists published surveillance guidelines (CARGs) intended to provide simplified, cost-effective and safe recommendations....