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David Kentner

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Citations 395
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Recent Articles
1.
Martano G, Delmotte N, Kiefer P, Christen P, Kentner D, Bumann D, et al.
Nat Protoc . 2014 Dec; 10(1):1-11. PMID: 25474028
Metabolomics has emerged as a powerful tool for addressing biological questions. Liquid chromatography coupled with mass spectrometry (LC-MS) is widely used for metabolic characterization, including targeted and untargeted approaches. Despite...
2.
Kentner D, Martano G, Callon M, Chiquet P, Brodmann M, Burton O, et al.
Proc Natl Acad Sci U S A . 2014 Jun; 111(27):9929-34. PMID: 24958876
Shigella flexneri proliferate in infected human epithelial cells at exceptionally high rates. This vigorous growth has important consequences for rapid progression to life-threatening bloody diarrhea, but the underlying metabolic mechanisms...
3.
Schonig K, Kentner D, Gossen M, Baldinger T, Miao J, Welzel K, et al.
Transgenic Res . 2010 Jul; 20(3):709-20. PMID: 20640885
The establishment of functional transgenic mouse lines is often limited by problems caused by integration site effects on the expression construct. Similarly, tetracycline (Tet) controlled transcription units most commonly used...
4.
Kentner D, Sourjik V
Annu Rev Microbiol . 2010 Jun; 64:373-90. PMID: 20528689
Following the introduction of fluorescent protein tags, the application of fluorescence microscopy in microbial cell biology has advanced the field dramatically. We now understand that bacterial cells are not simple...
5.
Weidenfeld I, Gossen M, Low R, Kentner D, Berger S, Gorlich D, et al.
Nucleic Acids Res . 2009 Mar; 37(7):e50. PMID: 19264799
Conditional gene expression systems have developed into essential tools for the study of gene functions. However, their utility is often limited by the difficulty of identifying clonal cell lines, in...
6.
Kentner D, Sourjik V
Mol Syst Biol . 2009 Jan; 5:238. PMID: 19156130
Protein-protein interactions play key roles in virtually all cellular processes, often forming complex regulatory networks. A powerful tool to study interactions in vivo is fluorescence resonance energy transfer (FRET), which...
7.
Schulmeister S, Ruttorf M, Thiem S, Kentner D, Lebiedz D, Sourjik V
Proc Natl Acad Sci U S A . 2008 Apr; 105(17):6403-8. PMID: 18427119
Signal processing in bacterial chemotaxis relies on large sensory complexes consisting of thousands of protein molecules. These clusters create a scaffold that increases the efficiency of pathway reactions and amplifies...
8.
Thiem S, Kentner D, Sourjik V
EMBO J . 2007 Mar; 26(6):1615-23. PMID: 17332753
Chemotaxis receptors and associated signalling proteins in Escherichia coli form clusters that consist of thousands of molecules and are the largest native protein complexes described to date in bacteria. Clusters...
9.
Kentner D, Sourjik V
Curr Opin Microbiol . 2006 Oct; 9(6):619-24. PMID: 17064953
Sensory complexes in bacterial chemotaxis are organized in large clusters, building complex signal-processing machinery. Interactions among chemoreceptors are the main determinant of cluster formation and create an allosteric network that...
10.
Kentner D, Thiem S, Hildenbeutel M, Sourjik V
Mol Microbiol . 2006 Jul; 61(2):407-17. PMID: 16856941
Chemotactic stimuli in bacteria are sensed by large sensory complexes, or receptor clusters, that consist of tens of thousands of proteins. Receptor clusters appear to play a key role in...