David J Pearton
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Explore the profile of David J Pearton including associated specialties, affiliations and a list of published articles.
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11
Citations
337
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Recent Articles
1.
Roussis I, Pearton D, Niazi U, Tsaknakis G, Papadopoulos G, Cook R, et al.
PLoS Genet
. 2025 Mar;
21(3):e1011617.
PMID: 40048486
Friend of GATA1 (FOG-1) is an essential transcriptional co-factor of the master erythroid transcription factor GATA1. The knockout of the Zfpm1 gene, coding for FOG-1, results in early embryonic lethality...
2.
Bunick C, Presland R, Lawrence O, Pearton D, Milstone L, Steitz T
J Invest Dermatol
. 2015 Mar;
135(7):1801-1809.
PMID: 25760235
The fused-type S100 protein profilaggrin and its proteolytic products including filaggrin are important in the formation of a normal epidermal barrier; however, the specific function of the S100 calcium-binding domain...
3.
Dhouailly D, Pearton D, Michon F
Dev Dyn
. 2014 Aug;
243(10):1226-41.
PMID: 25130543
Background: The cornea is an ectodermal/neural crest derivative formed through a cascade of molecular mechanisms to give rise to the specific optical features necessary for its refractory function. Moreover, during...
4.
Pearton D, Smith C, Redgate E, van Leeuwen J, Donnison M, Pfeffer P
Dev Biol
. 2014 May;
392(2):344-57.
PMID: 24859262
In mice the transcription factor Elf5 is necessary for correct trophoblast development. Upon knockdown of Elf5, TS cells display neither a decrease in proliferation nor an increase in cell death...
5.
Collomb E, Yang Y, Foriel S, Cadau S, Pearton D, Dhouailly D
Dev Dyn
. 2013 Jan;
242(5):401-13.
PMID: 23335276
Background: The corneal epithelium (CE) overlays a stroma, which is derived from neural crest cells, and appears to be committed during chick development, but appears still labile in adult rabbit....
6.
Pfeffer P, Pearton D
Reproduction
. 2012 Jan;
143(3):231-46.
PMID: 22223687
This review summarises current knowledge about the specification, commitment and maintenance of the trophoblast lineage in mice and cattle. Results from gene expression studies, in vivo loss-of-function models and in...
7.
Pearton D, Broadhurst R, Donnison M, Pfeffer P
Dev Biol
. 2011 Oct;
360(2):343-50.
PMID: 22020251
Mouse Elf5 is expressed exclusively in the trophectoderm from the late blastocyst stage to postgastrulation. We demonstrate here that the proximal promoter is used for trophectoderm expression but is not...
8.
Berg D, Smith C, Pearton D, Wells D, Broadhurst R, Donnison M, et al.
Dev Cell
. 2011 Feb;
20(2):244-55.
PMID: 21316591
The trophectoderm (TE) and inner cell mass (ICM) are committed and marked by reciprocal expression of Cdx2 and Oct4 in mouse late blastocysts. We find that the TE is not...
9.
Pearton D, Yang Y, Dhouailly D
Proc Natl Acad Sci U S A
. 2005 Mar;
102(10):3714-9.
PMID: 15738417
Differentiated cells of the corneal epithelium are converted to hair, along with their associated stem cells, then interfollicular epidermis, by means of a multistep process triggered by dermal developmental signals....
10.
Pearton D, Ferraris C, Dhouailly D
Int J Dev Biol
. 2004 Jul;
48(2-3):197-201.
PMID: 15272385
Corneal epithelium transdifferentiation into a hair-bearing epidermis provides a particularly useful system for studying the possibility that transient amplifying (TA) cells are able to activate different genetic programs in response...