David J Glass
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Explore the profile of David J Glass including associated specialties, affiliations and a list of published articles.
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122
Citations
10445
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Recent Articles
1.
Xu J, Wakai M, Xiong K, Yang Y, Prabakaran A, Wu S, et al.
Cell Rep
. 2025 Mar;
44(3):115403.
PMID: 40056415
Chronic inflammation and a decline in mitochondrial function are hallmarks of aging. Here, we show that the two mechanisms may be linked. We found that interleukin-6 (IL6) suppresses mitochondrial function...
2.
Egerman M, Zhang Y, Donne R, Xu J, Gadi A, McEwen C, et al.
Skelet Muscle
. 2025 Feb;
15(1):4.
PMID: 39994804
Background: Prior studies suggested that canonical Activin Receptor II (ActRII) and BMP receptor (BMPR) ligands can have opposing, distinct effects on skeletal muscle depending in part on differential downstream SMAD...
3.
Kessler M, Damask A, OKeeffe S, Banerjee N, Li D, Watanabe K, et al.
Nature
. 2025 Jan;
637(8047):E27.
PMID: 39779868
No abstract available.
4.
Johns N, Hatakeyama S, Stephens N, Degen M, Degen S, Frieauff W, et al.
PLoS One
. 2024 Dec;
19(12):e0314953.
PMID: 39621792
[This corrects the article DOI: 10.1371/journal.pone.0083618.].
5.
Wasserman J, Faezov B, Patel K, Kurimchak A, Palacio S, Glass D, et al.
Nat Commun
. 2024 Jul;
15(1):5776.
PMID: 38982062
The Ser/Thr protein phosphatase 2 A (PP2A) regulates the dephosphorylation of many phosphoproteins. Substrate recognition are mediated by B regulatory subunits. Here, we report the identification of a substrate conserved...
6.
Zhou Y, Zhao Y, Carbonaro M, Chen H, Germino M, Adler C, et al.
Metabolism
. 2024 Mar;
154:155830.
PMID: 38428673
Liver zonation characterizes the separation of metabolic pathways along the lobules and is required for optimal hepatic function. Wnt signaling is a master regulator of spatial liver zonation. A perivenous-periportal...
7.
Krais J, Glass D, Chudoba I, Wang Y, Feng W, Simpson D, et al.
Nat Commun
. 2023 Nov;
14(1):7714.
PMID: 38001070
Homologous recombination (HR)-deficiency induces a dependency on DNA polymerase theta (Polθ/Polq)-mediated end joining, and Polθ inhibitors (Polθi) are in development for cancer therapy. BRCA1 and BRCA2 deficient cells are thought...
8.
Yueh W, Glass D, Johnson N
J Mol Biol
. 2023 Nov;
436(1):168372.
PMID: 37979908
Brca1 mouse models were first reported in the mid-1990's shortly after cloning the human gene. Since then, many mouse models with a range of mutations have been generated, some mimic...
9.
Shavlakadze T, Xiong K, Mishra S, McEwen C, Gadi A, Wakai M, et al.
Skelet Muscle
. 2023 Jul;
13(1):11.
PMID: 37438807
Background: As a result of aging, skeletal muscle undergoes atrophy and a decrease in function. This age-related skeletal muscle weakness is known as "sarcopenia". Sarcopenia is part of the frailty...
10.