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David J Ellar

Explore the profile of David J Ellar including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 529
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Recent Articles
1.
Wang J, Chaudhuri R, Ellar D
Plasmid . 2009 Nov; 63(1):46-52. PMID: 19879290
A new insertion variant of IS231 family, designated ISBth4, was identified from Bacillus thuringiensis MEX312. ISBth4 is 2046bp in length and is delimited by two 17bp inverted repeats (IR) with...
2.
Rees J, Jarrett P, Ellar D
J Invertebr Pathol . 2009 Mar; 100(3):139-46. PMID: 19320042
In an effort to determine a reason for differing susceptibilities to Bacillus thuringiensis (Bt) Cry delta-endotoxins amongst lepidopteran species, the peritrophic membrane (PM), and a number of agents that target...
3.
Pigott C, King M, Ellar D
Appl Environ Microbiol . 2008 Apr; 74(11):3497-511. PMID: 18408065
Cry proteins are a large family of crystalline toxins produced by Bacillus thuringiensis. Individually, the family members are highly specific, but collectively, they target a diverse range of insects and...
4.
Wang J, Steggles J, Ellar D
FEMS Microbiol Lett . 2008 Jan; 280(1):127-34. PMID: 18218018
Sequence analysis of a virulence-attenuated Bacillus thuringiensis signature tagged mutant 6F8 led to the identification of an 18 182 bp locus encoding 29 potential protein-coding ORFs. Thirteen of the 29...
5.
Pinheiro V, Ellar D
Cell Microbiol . 2007 Jun; 9(10):2372-80. PMID: 17573906
Photorhabdus luminescens toxin complex (Tc) has been characterized as a potent three-component insecticidal protein complex. Homologues of genes encoding P. luminescens Tc components have been identified in several other enterobacteria...
6.
Pigott C, Ellar D
Microbiol Mol Biol Rev . 2007 Jun; 71(2):255-81. PMID: 17554045
Bacillus thuringiensis produces crystalline protein inclusions with insecticidal or nematocidal properties. These crystal (Cry) proteins determine a particular strain's toxicity profile. Transgenic crops expressing one or more recombinant Cry toxins...
7.
Ayra-Pardo C, Davis P, Ellar D
J Invertebr Pathol . 2007 Feb; 95(1):41-7. PMID: 17306294
Bacillus thuringiensis Cry1Ac toxin is 100 times less toxic than Cry1C to Mamestra brassicae. An R(423)S mutation abolishes Cry1Ac toxin proteolysis in M. brassicae gut juice but does not increase...
8.
Steggles J, Wang J, Ellar D
Curr Microbiol . 2006 Aug; 53(4):303-10. PMID: 16941243
Transposon Tn917 was used to identify Bacillus thuringiensis genes required for virulence and survival in a Manduca sexta (tobacco hornworm) septicaemia model. Uniquely tagged transposons, n = 72, were constructed...
9.
Pinheiro V, Ellar D
Cell Microbiol . 2006 Mar; 8(4):545-57. PMID: 16548881
All metazoans have evolved means to protect themselves from threats present in the environment: injuries, viruses, fungi, bacteria and other parasites. Insect protection includes innate physical barriers and both cellular...
10.
Gurkan C, Ellar D
Microb Cell Fact . 2005 Dec; 4:33. PMID: 16336647
The methylotrophic yeast Pichia pastoris is a popular heterologous expression host for the recombinant production of a variety of prokaryotic and eukaryotic proteins. The rapid emergence of P. pastoris as...