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David J Brenner

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Articles 252
Citations 7956
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Recent Articles
11.
Royba E, Shuryak I, Ponnaiya B, Repin M, Pampou S, Karan C, et al.
bioRxiv . 2024 Jun; PMID: 38854157
In cytogenetic biodosimetry, assessing radiation exposure typically requires over 48 hours for cells to reach mitosis, significantly delaying the administration of crucial radiation countermeasures needed within the first 24 hours...
12.
Chen Z, Li X, Brenner D, Hellebust T, Hoskin P, Joiner M, et al.
Med Phys . 2024 May; 51(6):3850-3923. PMID: 38721942
Brachytherapy utilizes a multitude of radioactive sources and treatment techniques that often exhibit widely different spatial and temporal dose delivery patterns. Biophysical models, capable of modeling the key interacting effects...
13.
Welch D, Hashmi R, Petersen C, Erde S, Brenner D, Nardell E
Photochem Photobiol . 2024 May; 101(1):157-166. PMID: 38702942
Far-UVC radiation between 200 and 230 nm is a promising technology for reducing airborne disease transmission. Previous work with far-UVC lamps has demonstrated the efficacy of far-UVC radiation to inactivate...
14.
Harken A, Deoli N, Perez Campos C, Ponnaiya B, Garty G, Lee G, et al.
Biomed Opt Express . 2024 Apr; 15(4):2561-2577. PMID: 38633084
To improve particle radiotherapy, we need a better understanding of the biology of radiation effects, particularly in heavy ion radiation therapy, where global responses are observed despite energy deposition in...
15.
Repin M, Garty G, Garippa R, Brenner D
Radiat Res . 2024 Mar; 201(6):567-571. PMID: 38514936
Micronuclei, detected through the cytokinesis-block micronucleus assay, are valuable indicators of ionizing radiation exposure, especially in short-term lymphocyte cultures. The peripheral human blood lymphocyte assay is recognized as a prime...
16.
Buonanno M, Kleiman N, Welch D, Hashmi R, Shuryak I, Brenner D
Sci Rep . 2024 Mar; 14(1):6722. PMID: 38509265
An emerging intervention for control of airborne-mediated pandemics and epidemics is whole-room far-UVC (200-235 nm). Laboratory studies have shown that 222-nm light inactivates airborne pathogens, potentially without harm to exposed...
17.
Wang E, Shuryak I, Brenner D
Sci Rep . 2023 Dec; 13(1):21841. PMID: 38071393
The biological effects of densely-ionizing radiations such as neutrons and heavy ions encountered in space travel, nuclear incidents, and cancer radiotherapy, significantly differ from those of sparsely-ionizing photons and necessitate...
18.
Brenner D
Photochem Photobiol . 2023 Dec; 100(5):1186-1190. PMID: 38037431
There has been much recent interest in whole-room far-UVC (wavelength around 222 nm) to markedly and safely reduce overall levels of airborne pathogens in occupied indoor locations. Far-UVC light produces...
19.
Gorlitz M, Justen L, Rochette P, Buonanno M, Welch D, Kleiman N, et al.
Photochem Photobiol . 2023 Nov; 100(3):501-520. PMID: 37929787
The COVID-19 pandemic underscored the crucial importance of enhanced indoor air quality control measures to mitigate the spread of respiratory pathogens. Far-UVC is a type of germicidal ultraviolet technology, with...
20.
Kanagaraj K, Phillippi M, Narayan P, Szolc B, Perrier J, McLane A, et al.
Cytogenet Genome Res . 2023 Oct; 163(3-4):121-130. PMID: 37793357
The cytokinesis-block micronucleus (CBMN) assay is an established method for assessing chromosome damage in human peripheral blood lymphocytes resulting from exposure to genotoxic agents such as ionizing radiation. The objective...