David Houghton
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Explore the profile of David Houghton including associated specialties, affiliations and a list of published articles.
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47
Citations
863
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Recent Articles
1.
Houghton D, Shannon O, Chater P, Wilcox M, Pearson J, Stanforth K, et al.
Gut Microbiome (Camb)
. 2024 Sep;
4:e8.
PMID: 39295906
White kidney bean extract (WKBE) is a nutraceutical often advocated as an anti-obesity agent. The main proposed mechanism for these effects is alpha-amylase inhibition, thereby slowing carbohydrate digestion and absorption....
2.
Houghton D, Ng Y, Jackson M, Stefanetti R, Hynd P, Mac Aogain M, et al.
Gastro Hep Adv
. 2024 Aug;
1(4):666-677.
PMID: 39132075
Background And Aims: Gastrointestinal (GI) dysmotility is a common and debilitating clinical manifestation in patients with mitochondrial DNA (mtDNA)-related disease with no curative and few effective symptomatic therapies. A low-residue...
3.
Jordan C, Charman S, Batterham A, Flynn D, Houghton D, Errington L, et al.
Heart
. 2023 Feb;
109(18):1357-1362.
PMID: 36849238
Objective: To conduct a systematic review and meta-analysis to quantify habitual physical activity (PA) levels of patients with heart failure (HF) and assess the quality of reporting of device-assessed PA....
4.
Li L, Houghton D, Lietz G, Watson A, Stewart C, Bal W, et al.
Nutrients
. 2022 Nov;
14(22).
PMID: 36432574
Diets rich in whole grains are associated with improved health and a lower risk of non-communicable diseases, but the mechanisms through which these health benefits are conveyed are uncertain. One...
5.
Kimble R, Gouinguenet P, Ashor A, Stewart C, Deighton K, Matu J, et al.
Crit Rev Food Sci Nutr
. 2022 Apr;
63(27):8698-8719.
PMID: 35361035
Consumption of the Mediterranean dietary pattern (MedDiet) is associated with reduced risk of numerous non-communicable diseases. Modulation of the composition and metabolism of the gut microbiota represents a potential mechanism...
6.
Smith A, Whitehall J, Bradshaw C, Gay D, Robertson F, Blain A, et al.
Nat Cancer
. 2022 Feb;
2(1):129.
PMID: 35121898
No abstract available.
7.
Stamp C, Whitehall J, Smith A, Houghton D, Bradshaw C, Stoll E, et al.
Aging Cell
. 2021 Feb;
20(3):e13321.
PMID: 33626245
One of the hallmarks of aging is an accumulation of cells with defects in oxidative phosphorylation (OXPHOS) due to mutations of mitochondrial DNA (mtDNA). Rapidly dividing tissues maintained by stem...
8.
Smith A, Whitehall J, Bradshaw C, Gay D, Robertson F, Blain A, et al.
Nat Cancer
. 2020 Oct;
1(10):976-989.
PMID: 33073241
Oxidative phosphorylation (OXPHOS) defects caused by somatic mitochondrial DNA (mtDNA) mutations increase with age in human colorectal epithelium and are prevalent in colorectal tumours, but whether they actively contribute to...
9.
Dalton C, Milinis K, Houghton D, Ridley P, Davies K, Williams R, et al.
Eur J Surg Oncol
. 2020 Sep;
46(11):2042-2049.
PMID: 32893045
Introduction: We describe the 5-year oncological and functional outcomes of transoral laser microsurgery, neck dissection (TLM + ND) and adjuvant radiotherapy (PORT) used to treat patients with oropharyngeal carcinoma. The...
10.
Werner C, Mathkour M, Scullen T, Houghton D, Lea G, Dallapiazza R, et al.
World Neurosurg
. 2020 Aug;
144:e347-e352.
PMID: 32853766
Objective: Advancing age and greater number of medical comorbidities are well-known risk factors for higher rates of surgical complications and undesirable outcomes. We sought to determine the risk of increasing...