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David Head

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Articles 27
Citations 567
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Recent Articles
1.
Hughes M, Cook K, Cussons S, Boroumand A, Tyler A, Head D, et al.
Small . 2024 Nov; 21(1):e2407090. PMID: 39533485
The structural evolution of hierarchical structures of nanoscale biomolecules is crucial for the construction of functional networks in vivo and in vitro. Despite the ubiquity of these networks, the physical...
2.
Hughes M, West D, Wurr R, Cussons S, Cook K, Mahmoudi N, et al.
J Colloid Interface Sci . 2024 Oct; 678(Pt C):1259-1269. PMID: 39357245
Folded protein hydrogels are emerging as promising new materials for medicine and healthcare applications. Folded globular proteins can be modelled as colloids which exhibit site specific cross-linking for controlled network...
3.
Yeung T, Zhang Y, Kennedy B, Walsh C, Love T, Xia D, et al.
J Pathol . 2024 May; 263(3):386-395. PMID: 38801208
While increased DNA damage is a well-described feature of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), it is unclear whether all lineages and all regions of the marrow are...
4.
Cook K, Head D, Dougan L
Soft Matter . 2023 Mar; 19(15):2780-2791. PMID: 36988480
Globular folded protein-based hydrogels are becoming increasingly attractive due to their specific biological functionality, as well as their responsiveness to stimuli. By modelling folded proteins as colloids, there are rich...
5.
Head D
Phys Rev Lett . 2022 Jul; 129(1):018001. PMID: 35841566
A family of marginally rigid (isostatic) spring networks with fractal structure up to a controllable length was devised, and the viscoelastic spectra G^{*}(ω) calculated. Two nontrivial scaling regimes were observed,...
6.
Greenberg P, Stone R, Al-Kali A, Bennett J, Borate U, Brunner A, et al.
J Natl Compr Canc Netw . 2022 Feb; 20(2):106-117. PMID: 35130502
The NCCN Guidelines for Myelodysplastic Syndromes (MDS) provide recommendations for the evaluation, diagnosis, and management of patients with MDS based on a review of clinical evidence that has led to...
7.
Head D, Storm C
Phys Rev Lett . 2019 Dec; 123(23):238005. PMID: 31868451
We employ a matrix-based solver for the linear rheology of fluid-immersed disordered spring networks to reveal four distinct dynamic response regimes. One regime-completely absent in the known vacuum response-exhibits coupled...
8.
Hanson B, Head D, Dougan L
Soft Matter . 2019 Oct; 15(43):8778-8789. PMID: 31595281
Biological organisms make use of hierarchically organised structures to modulate mechanical behaviour across multiple lengthscales, allowing microscopic objects to generate macroscopic effects. Within these structural hierarchies, the resultant physical behaviour...
9.
Head D, Devine D, Marsh P
Sci Rep . 2017 Dec; 7(1):17413. PMID: 29234121
Dental caries is the most prevalent infection globally and a substantial economic burden in developed countries. Dietary sugars are the main risk factor, and drive increased proportions of acid-producing and...
10.
Nedelcu E, Desai M, Green J, Bensing K, Turner A, Head D, et al.
Transfusion . 2017 Oct; 58(1):176-180. PMID: 29023757
Background: Autoimmune hemolytic anemia (AIHA) due to anti-En has been previously reported in association with massive intravascular hemolysis, disseminated intravascular coagulation, and fatal outcomes. Here we report a case of...