David Hackett
Overview
Explore the profile of David Hackett including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
21
Citations
484
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0
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Recent Articles
1.
Niepsch D, Randviir E, Murphy-Peers R, Coulthard E, Hackett D, McKendry D, et al.
J Environ Manage
. 2025 Mar;
380:124928.
PMID: 40086284
By 2050, 90% of the Earth's topsoil is considered 'at risk' (according to the UN). Within the UK, more than 6 million hectares are at risk of compaction or erosion...
2.
Thinnes C, Waschkowitz R, Courtney E, Culligan E, Fahy K, Ferrazza R, et al.
bioRxiv
. 2025 Feb;
PMID: 39990405
The human microbiome plays a crucial role in metabolism and thereby influences health and disease. Constraint-based reconstruction and analysis (COBRA) has proven an attractive framework to generate mechanism-derived hypotheses along...
3.
Vickers S, Hackett D, Murray F, Hutson P, Heal D
J Psychopharmacol
. 2015 Nov;
29(12):1290-307.
PMID: 26589243
Binge-eating disorder is a common psychiatric disorder affecting ~2% of adults. Binge-eating was initiated in freely-fed, lean, adult, female rats by giving unpredictable, intermittent access to ground, milk chocolate over...
4.
5.
Rowley H, Kulkarni R, Gosden J, Brammer R, Hackett D, Heal D
J Psychopharmacol
. 2013 Dec;
28(3):254-69.
PMID: 24327450
Lisdexamfetamine dimesylate is a novel prodrug approved in North America, Europe and Brazil for treating attention deficit hyperactivity disorder (ADHD). It undergoes rate-limited hydrolysis by red blood cells to yield...
6.
Heal D, Buckley N, Gosden J, Slater N, France C, Hackett D
Neuropharmacology
. 2013 Jun;
73:348-58.
PMID: 23748096
Lisdexamfetamine dimesylate, which consists of L-lysine covalently bound to D-amfetamine, is the first prodrug for treating ADHD. Its metabolic conversion to yield D-amfetamine by rate-limited, enzymatic hydrolysis is unusual because...
7.
Sen S, Asrress K, Nijjer S, Petraco R, Malik I, Foale R, et al.
J Am Coll Cardiol
. 2013 Mar;
61(13):1409-20.
PMID: 23500218
Objectives: This study sought to determine if adenosine administration is required for the pressure-only assessment of coronary stenoses. Background: The instantaneous wave-free ratio (iFR) is a vasodilator-free pressure-only measure of...
8.
Qureshi S, Hildick-Smith D, de Giovanni J, Clift P, Stuart G, Henderson R, et al.
Cardiol Young
. 2012 May;
23(1):68-74.
PMID: 22583564
In order to optimise care of the adult patients with complex congenital heart disease, there is a need to develop recommendations for interventions. This document is the work of representatives...
9.
Sen S, Escaned J, Malik I, Mikhail G, Foale R, Mila R, et al.
J Am Coll Cardiol
. 2011 Dec;
59(15):1392-402.
PMID: 22154731
Objectives: The purpose of this study was to develop an adenosine-independent, pressure-derived index of coronary stenosis severity. Background: Assessment of stenosis severity with fractional flow reserve (FFR) requires that coronary...
10.
Smith D, Toff W, Joy M, Dowdall N, Johnston R, Clark L, et al.
Heart
. 2010 Jul;
96 Suppl 2:ii1-16.
PMID: 20644218
No abstract available.