David Hackam
Overview
Explore the profile of David Hackam including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
399
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Recent Articles
1.
Steen E, Moles C, Goldstein A, Morowitz M, Gosain A, Mollen K, et al.
J Surg Res
. 2019 Jul;
244:502-508.
PMID: 31330294
Background: Pediatric surgeons have long been advocates of basic science research. However, new challenges facing the scientific community have threatened the success of academic surgeons pursuing basic science careers. The...
2.
Challenges in Diagnosis and Management of Pancreatic Inflammatory Myofibroblastic Tumors in Children
Berhe S, Goldstein S, Thompson E, Hackam D, Rhee D, Nasr I
Pancreas
. 2019 Apr;
48(4):e27-e29.
PMID: 30973469
No abstract available.
3.
Hackam D, Caplan M
Semin Pediatr Surg
. 2017 Dec;
27(1):11-18.
PMID: 29275810
Necrotizing enterocolitis (NEC) continues to afflict approximately 7% of preterm infants born weighing less than 1500g, though recent investigations have provided novel insights into the pathogenesis of this complex disease....
4.
Dziki J, Keane T, Shaffiey S, Cognetti D, Turner N, Nagle D, et al.
J Surg Res
. 2017 Oct;
218:353-360.
PMID: 28985874
Precancerous or cancerous lesions of the gastrointestinal tract often require surgical resection via endomucosal resection. Although excision of the colonic mucosa is an effective cancer treatment, removal of large lesions...
5.
Costello C, Phillipsen M, Hartmanis L, Kwasnica M, Chen V, Hackam D, et al.
Sci Rep
. 2017 Oct;
7(1):12515.
PMID: 28970586
The development of in vitro artificial small intestines that realistically mimic in vivo systems will enable vast improvement of our understanding of the human gut and its impact on human...
6.
Haileselassie B, Su E, Pozios I, Nino D, Liu H, Lu D, et al.
Intensive Care Med Exp
. 2017 Apr;
5(1):21.
PMID: 28405943
Background: Recognition of cardiomyopathy in sepsis can be challenging due to the limitations of conventional measures such as ejection fraction (EF) and fractional shortening (FS) in the context of variable...
7.
Costello C, Hongpeng J, Shaffiey S, Yu J, Jain N, Hackam D, et al.
Biotechnol Bioeng
. 2014 Jan;
111(6):1222-32.
PMID: 24390638
In vitro intestinal models can provide new insights into small intestinal function, including cellular growth and proliferation mechanisms, drug absorption capabilities, and host-microbial interactions. These models are typically formed with...
8.
Deng M, Scott M, Loughran P, Gibson G, Sodhi C, Watkins S, et al.
J Immunol
. 2013 Apr;
190(10):5152-60.
PMID: 23562812
The morbidity associated with bacterial sepsis is the result of host immune responses to pathogens, which are dependent on pathogen recognition by pattern recognition receptors, such as TLR4. TLR4 is...
9.
Arciero J, Mi Q, Branca M, Hackam D, Swigon D
Wound Repair Regen
. 2013 Feb;
21(2):256-65.
PMID: 23421747
A two-dimensional continuum model of collective cell migration is used to predict the closure of gaps in intestinal epithelial cell layers. The model assumes that cell migration is governed by...
10.
Arciero J, Ermentrout G, Siggers R, Afrazi A, Hackam D, Vodovotz Y, et al.
J Theor Biol
. 2012 Dec;
321:83-99.
PMID: 23238281
Necrotizing enterocolitis (NEC) is a severe disease of the gastrointestinal tract in premature infants, characterized by a disrupted intestinal epithelium and an exaggerated pro-inflammatory response. Since the activation of Toll-like...