David H Wyllie
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Explore the profile of David H Wyllie including associated specialties, affiliations and a list of published articles.
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56
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2635
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Recent Articles
1.
Hilton B, Wilson D, OConnell A, Ironmonger D, Rudkin J, Allen N, et al.
Sci Rep
. 2023 Jan;
13(1):496.
PMID: 36627297
Understanding the genetic and environmental risk factors for serious bacterial infections in ageing populations remains incomplete. Utilising the UK Biobank (UKB), a prospective cohort study of 500,000 adults aged 40-69 ...
2.
Impact of antibiotic use on patient-level risk of death in 36 million hospital admissions in England
Budgell E, Davies T, Donker T, Hopkins S, Wyllie D, Peto T, et al.
J Infect
. 2021 Dec;
84(3):311-320.
PMID: 34963640
Objectives: Initiatives to curb hospital antibiotic use might be associated with harm from under-treatment. We examined the extent to which variation in hospital antibiotic prescribing is associated with mortality risk...
3.
Riste M, Davda P, Smith E, Wyllie D, Dedicoat M, Jog S, et al.
BMC Infect Dis
. 2021 Feb;
21(1):151.
PMID: 33546627
Background: Joint replacement is an effective intervention and prosthetic joint infection (PJI) is one of the most serious complications of such surgery. Diagnosis of PJI is often complex and requires...
4.
Mulchandani R, Jones H, Taylor-Phillips S, Shute J, Perry K, Jamarani S, et al.
BMJ
. 2020 Nov;
371:m4262.
PMID: 33177070
Objective: To assess the accuracy of the AbC-19 Rapid Test lateral flow immunoassay for the detection of previous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Design: Test accuracy study....
5.
Armstrong J, Rudkin J, Allen N, Crook D, Wilson D, Wyllie D, et al.
Microb Genom
. 2020 Jun;
6(7).
PMID: 32553051
UK Biobank (UKB) is an international health resource enabling research into the genetic and lifestyle determinants of common diseases of middle and older age. It comprises 500 000 participants. Public...
6.
Li Y, James S, Wyllie D, Wynne C, Czibula A, Bukhari A, et al.
Proc Natl Acad Sci U S A
. 2019 Jul;
116(33):16479-16488.
PMID: 31346090
Regulation of IFN signaling is critical in host recognition and response to pathogens while its dysregulation underlies the pathogenesis of several chronic diseases. STimulator of IFN Genes (STING) has been...
7.
Young B, Earle S, Soeng S, Sar P, Kumar V, Hor S, et al.
Elife
. 2019 Feb;
8.
PMID: 30794157
Pyomyositis is a severe bacterial infection of skeletal muscle, commonly affecting children in tropical regions, predominantly caused by . To understand the contribution of bacterial genomic factors to pyomyositis, we...
8.
Flaxman A, Yamaguchi Y, van Diemen P, Rollier C, Allen E, Elshina E, et al.
Vaccine
. 2018 Dec;
37(3):494-501.
PMID: 30503080
Introduction: S. aureus is a pathogen to which individuals are exposed shortly after birth, with immune responses to S. aureus increasing during childhood. There is marked heterogeneity between the anti-...
9.
Elshina E, Allen E, Flaxman A, van Diemen P, Milicic A, Rollier C, et al.
Vaccine
. 2018 Dec;
37(3):502-509.
PMID: 30502067
Introduction: There is a need for an efficacious vaccine reducing infections due to Staphylococcus aureus, a common cause of community and hospital infection. Infecting organisms originate from S. aureus populations...
10.
Wyllie D, Robinson E, Peto T, Crook D, Ajileye A, Rathod P, et al.
J Clin Microbiol
. 2018 Sep;
56(11).
PMID: 30209183
The detection of laboratory cross-contamination and mixed tuberculosis infections is an important goal of clinical mycobacteriology laboratories. The objective of this study was to develop a method to detect mixtures...