David H Coy
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Explore the profile of David H Coy including associated specialties, affiliations and a list of published articles.
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71
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Recent Articles
11.
Sun G, Mackey L, Coy D, Yu C, Sun L
J Cancer
. 2015 Sep;
6(10):996-1004.
PMID: 26366213
Hepatocellular carcinoma (HCC) is a type of malignant cancer. Notch signaling is aberrantly expressed in HCC tissues with more evidence showing that this signaling plays a critical role in HCCs....
12.
Sun L, Qian Q, Sun G, Mackey L, Fuselier J, Coy D, et al.
J Drug Target
. 2015 Jul;
24(2):169-77.
PMID: 26211366
Background: Human pancreatic carcinoids, a type of neuroendocrine tumors, are asymptomatic and difficult to diagnose, with the effects of traditional anti-cancer therapies being limited. The histone deacetylase (HDAC) inhibitor valproic...
13.
Sun L, Yu C, Mackey L, Coy D
Curr Top Med Chem
. 2015 Jul;
16(2):133-40.
PMID: 26126910
Multiple Gαi protein-coupled somatostatin receptors (SSTRs) are expressed in human kidney and liver tissues. Also, aberrant cAMP signaling has been shown to play a critical role in cysto-genesis and enlargement...
14.
Ramos-Alvarez I, Moreno P, Mantey S, Nakamura T, Nuche-Berenguer B, Moody T, et al.
Peptides
. 2015 May;
72:128-44.
PMID: 25976083
This following article is written for Prof. Abba Kastin's Festschrift, to add to the tribute to his important role in the advancement of the role of peptides in physiological, as...
15.
Ramos-Alvarez I, Mantey S, Nakamura T, Nuche-Berenguer B, Moreno P, Moody T, et al.
Peptides
. 2015 Feb;
66:26-42.
PMID: 25698233
Pituitary adenylate cyclase-activating polypeptide (PACAP) has widespread physiological/pathophysiological actions and there is increased interest for its use therapeutically, especially in the CNS (neuroprotection). Unfortunately, no selective PACAP-analogs exist for PACAP-preferring...
16.
Sun L, Sun G, Yu Y, Coy D
Anticancer Agents Med Chem
. 2015 Feb;
15(7):809-15.
PMID: 25642981
Hepatocellular carcinoma (HCC) is one of the most malignant cancers, with the second highest cancer death rate world-wide, next to lung cancer. The signaling mechanisms in HCC are currently not...
17.
Khan A, Maderdrut J, Li M, Toliver H, Coy D, Simon E, et al.
Physiol Rep
. 2014 Jan;
1(6):e00163.
PMID: 24400164
We determined whether pituitary adenylate cyclase-activating polypeptide 38 (PACAP38) prevents contrast-induced nephropathy using human renal proximal tubule epithelial (HK-2) cells and homozygous endothelial nitric oxide synthase-deficient (eNOS(-/-)) mice as a...
18.
Moreno P, Mantey S, Nuche-Berenguer B, Reitman M, Gonzalez N, Coy D, et al.
J Pharmacol Exp Ther
. 2013 Jul;
347(1):100-16.
PMID: 23892571
Bombesin-receptor-subtype-3 (BRS-3) is an orphan G-protein-coupled receptor of the bombesin (Bn) family whose natural ligand is unknown and which does not bind any natural Bn-peptide with high affinity. It is...
19.
Karimian N, Qin T, Liang T, Osundiji M, Huang Y, Teich T, et al.
Diabetes
. 2013 May;
62(8):2968-77.
PMID: 23630299
Impaired counterregulation during hypoglycemia in type 1 diabetes (T1D) is partly attributable to inadequate glucagon secretion. Intra-islet somatostatin (SST) suppression of hypoglycemia-stimulated α-cell glucagon release plays an important role. We...
20.
Tsai C, Leslie J, Franko-Tobin L, Prasnal M, Yang T, Mackey L, et al.
Arch Gynecol Obstet
. 2013 Feb;
288(2):393-400.
PMID: 23435724
Purpose: We investigated the effects of the anti-epilepsy drug valproic acid (VPA) alone and in combination in treating cervical cancer. Methods: VPA was investigated for its effects on cervical cancer...