David G Maranon
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Explore the profile of David G Maranon including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
458
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0
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Recent Articles
11.
Zhao W, Steinfeld J, Liang F, Chen X, Maranon D, Ma C, et al.
Nature
. 2017 Oct;
550(7676):360-365.
PMID: 28976962
The tumour suppressor complex BRCA1-BARD1 functions in the repair of DNA double-stranded breaks by homologous recombination. During this process, BRCA1-BARD1 facilitates the nucleolytic resection of DNA ends to generate a...
12.
Liang F, Longerich S, Miller A, Tang C, Buzovetsky O, Xiong Y, et al.
Cell Rep
. 2016 May;
15(10):2118-2126.
PMID: 27239033
The UAF1-USP1 complex deubiquitinates FANCD2 during execution of the Fanconi anemia DNA damage response pathway. As such, UAF1 depletion results in persistent FANCD2 ubiquitination and DNA damage hypersensitivity. UAF1-deficient cells...
13.
Parplys A, Zhao W, Sharma N, Groesser T, Liang F, Maranon D, et al.
Nucleic Acids Res
. 2015 Sep;
43(20):9817-34.
PMID: 26323318
NUCKS1 (nuclear casein kinase and cyclin-dependent kinase substrate 1) is a 27 kD chromosomal, vertebrate-specific protein, for which limited functional data exist. Here, we demonstrate that NUCKS1 shares extensive sequence...
14.
Zhao W, Vaithiyalingam S, San Filippo J, Maranon D, Jimenez-Sainz J, Fontenay G, et al.
Mol Cell
. 2015 Jul;
59(2):176-87.
PMID: 26145171
The tumor suppressor BRCA2 is thought to facilitate the handoff of ssDNA from replication protein A (RPA) to the RAD51 recombinase during DNA break and replication fork repair by homologous...
15.
Zahran S, Snodgrass J, Maranon D, Upadhyay C, Granger D, Bailey S
Proc Natl Acad Sci U S A
. 2015 Mar;
112(9):E928-36.
PMID: 25730846
Research links psychosocial stress to premature telomere shortening and accelerated human aging; however, this association has only been demonstrated in so-called "WEIRD" societies (Western, educated, industrialized, rich, and democratic), where...
16.
Quimby J, Maranon D, Battaglia C, McLeland S, Brock W, Bailey S
Am J Physiol Renal Physiol
. 2013 May;
305(3):F295-303.
PMID: 23720342
Telomeres are protective structures at the ends of chromosomes that have important implications for aging. To address the question of whether telomeres contribute to feline chronic kidney disease (CKD), we...
17.
Le P, Maranon D, Altina N, Battaglia C, Bailey S
Front Oncol
. 2013 Apr;
3:91.
PMID: 23616949
Maintenance of telomeres, repetitive elements at eukaryotic chromosomal termini, and the end-capping structure and function they provide, are imperative for preserving genome integrity and stability. The discovery that telomeres are...