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David G Besselsen

Explore the profile of David G Besselsen including associated specialties, affiliations and a list of published articles. Areas
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Articles 67
Citations 1371
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Recent Articles
1.
Ignatenko N, Trinh H, Wagner A, Gerner E, Bime C, Hsu C, et al.
bioRxiv . 2025 Mar; PMID: 40060444
Despite numerous research efforts and several effective vaccines and therapies developed against COronaVIrus Disease 2019 (COVID-19), drug repurposing remains an attractive alternative to identify new treatments for SARS-CoV-2 virus variants...
2.
Montague J, Hutchens G, Howard C, Rice P, Besselsen D, Slayton M, et al.
Lasers Surg Med . 2024 Dec; 57(2):204-218. PMID: 39702990
Objectives: To study the healing response of rat Achilles tendon when lacerated or treated with intense therapeutic ultrasound (ITU) via utilization of multiphoton microscopy (MPM) imaging and histology. Materials And...
3.
Georgieva T, Darmoul D, Chen H, Cui H, Rice P, Barton J, et al.
Cancers (Basel) . 2024 Nov; 16(22). PMID: 39594797
Background/objectives: The objective of this study was to assess the role of a secreted serine protease, kallikrein-related peptidase 6 (KLK6), during colorectal tumorigenesis driven by a mutant tumor suppressor gene....
4.
Wagner A, Romero-Aleshire M, Billheimer D, Henderson K, Besselsen D
Comp Med . 2024 May; 74(3):156-166. PMID: 38714354
Genomic sequence analysis of autonomous parvoviruses within the genus generates 2 groups that are principally of mouse origin: the minute virus of mice (MVM) strains (MVMp, MVMi, MVMc, MVMm) and...
5.
Sheikh I, Bianchi-Smak J, Laubitz D, Schiro G, Midura-Kiela M, Besselsen D, et al.
Gut Microbes . 2024 Mar; 16(1):2333483. PMID: 38532703
Although the role of the intestinal microbiota in the pathogenesis of inflammatory bowel disease (IBD) is beyond debate, attempts to verify the causative role of IBD-associated dysbiosis have been limited...
6.
Jergovic M, Coplen C, Uhrlaub J, Besselsen D, Cheng S, Smithey M, et al.
Nat Commun . 2024 Jan; 15(1):470. PMID: 38212327
No abstract available.
7.
Laubitz D, Gurney M, Midura-Kiela M, Clutter C, Besselsen D, Chen H, et al.
Sci Rep . 2022 Aug; 12(1):14725. PMID: 36042372
Dysregulation of intra- and extracellular pH in cancer contributes to extracellular matrix remodeling, favors cell migration, proliferation, and metastasis. Although the primary attention has been focused on the role of...
8.
Jergovic M, Coplen C, Uhrlaub J, Besselsen D, Cheng S, Smithey M, et al.
Nat Commun . 2021 Sep; 12(1):5303. PMID: 34489451
Naïve T (Tn) cells require two homeostatic signals for long-term survival: tonic T cell receptor:self-peptide-MHC contact and IL-7 stimulation. However, how microbial exposure impacts Tn homeostasis is still unclear. Here...
9.
Daines M, Pereira R, Cunningham A, Pryor B, Besselsen D, Liu Y, et al.
Front Cell Infect Microbiol . 2021 Sep; 11:683194. PMID: 34485171
is a ubiquitous fungus and a major allergen associated with the development of asthma. Inhalation of intact spores is the primary cause of human exposure to fungal allergen. However, allergen-rich...
10.
Bartlett M, Flores A, Ye T, Smidt S, Dollish H, Stancati J, et al.
Exp Neurol . 2020 Jul; 333:113413. PMID: 32717354
Parkinson's disease (PD) is the second most common neurodegenerative disease. Pharmacotherapy with L-DOPA remains the gold-standard therapy for PD, but is often limited by the development of the common side...