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David Fielding

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Articles 68
Citations 423
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Recent Articles
1.
Afridi W, Picos S, Bark J, Stamoudis D, Vasani S, Irwin D, et al.
Cancer Metastasis Rev . 2025 Jan; 44(1):29. PMID: 39888565
CT chest scans are commonly performed worldwide, either in routine clinical practice for a wide range of indications or as part of lung cancer screening programs. Many of these scans...
2.
Liu L, Zhang J, Wood S, Newell F, Leonard C, Koufariotis L, et al.
BMC Genomics . 2024 Sep; 25(1):898. PMID: 39350042
Background: Lung cancer is a heterogeneous disease and the primary cause of cancer-related mortality worldwide. Somatic mutations, including large structural variants, are important biomarkers in lung cancer for selecting targeted...
3.
Zhou Q, Niu X, Zhang Z, OByrne K, Kulasinghe A, Fielding D, et al.
Adv Sci (Weinh) . 2024 Jun; 11(33):e2401818. PMID: 38885350
Glycosylation is the most common post-translational modification of proteins and regulates a myriad of fundamental biological processes under normal, and pathological conditions. Altered protein glycosylation is linked to malignant transformation,...
4.
Chaddha U, Agrawal A, Kurman J, Ortiz-Comino R, Dutau H, Freitag L, et al.
Respirology . 2024 May; 29(7):563-573. PMID: 38812262
Malignant Central Airway Obstruction (MCAO) encompasses significant and symptomatic narrowing of the central airways that can occur due to primary lung cancer or metastatic disease. Therapeutic bronchoscopy is associated with...
5.
Steinfort D, Kothari G, Wallace N, Hardcastle N, Rangamuwa K, Dieleman E, et al.
Lancet Respir Med . 2024 Mar; 12(6):467-475. PMID: 38490228
Background: Systematic mediastinal lymph node staging by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) improves accuracy of staging in patients with early-stage non-small-cell lung cancer (NSCLC). However, patients with locally advanced...
6.
Chew R, Tozer S, Ulett K, Paterson D, Whiley D, Sloots T, et al.
Open Forum Infect Dis . 2024 Mar; 11(3):ofae071. PMID: 38444816
Using nasopharyngeal (NP) swab samples instead of lower respiratory tract specimens for polymerase chain reaction (PCR) to diagnose pneumonia (PJP) may be better tolerated and improve diagnostic accessibility. In this...
7.
Fielding D, Lakis V, Dalley A, Chittoory H, Newell F, Koufariotis L, et al.
Cancers (Basel) . 2024 Feb; 16(4). PMID: 38398180
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is often the only source of tumor tissue from patients with advanced, inoperable lung cancer. EBUS-TBNA aspirates are used for the diagnosis, staging, and...
8.
Fielding D, van der Heijden E
Respirology . 2024 Feb; 29(4):274-276. PMID: 38326225
No abstract available.
9.
Das U, Fielding D
Sci Rep . 2024 Jan; 14(1):1382. PMID: 38228678
Ebola is a highly infectious and often fatal zoonotic disease endemic to West and Central Africa. Local outbreaks of the disease are common, but the largest recorded Ebola epidemic originated...
10.
Fielding D, Dalley A, Singh M, Nandakumar L, Lakis V, Chittoory H, et al.
Front Oncol . 2023 Nov; 13:1259882. PMID: 37927461
Introduction: Tumour Mutation Burden (TMB) is a potential biomarker for immune cancer therapies. Here we investigated parameters that might affect TMB using duplicate cytology smears obtained from endobronchial ultrasound transbronchial...