David E Ott
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Explore the profile of David E Ott including associated specialties, affiliations and a list of published articles.
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1721
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Recent Articles
1.
Trivett M, Burke J, Deleage C, Coren L, Hill B, Jain S, et al.
J Virol
. 2019 Aug;
93(21).
PMID: 31434738
doptive ell ransfer (ACT) is a powerful experimental approach to directly study T-cell-mediated immunity In the rhesus macaque AIDS virus model, infusing simian immunodeficiency virus (SIV)-infected animals with CD8 T...
2.
A PLPPV sequence in the p8 region of Gag provides late domain function for mouse mammary tumor virus
Coren L, Nagashima K, Ott D
Virology
. 2019 Jul;
535:272-278.
PMID: 31357166
The late (L) domain sequence used by mouse mammary tumor virus (MMTV) remains undefined. Similar to other L domain-containing proteins, MMTV p8 and p14 proteins are monoubiquitinated, suggesting L domain...
3.
Miller Jenkins L, Paine E, Deshmukh L, Nikolayevskiy H, Lyons G, Scerba M, et al.
J Am Chem Soc
. 2019 May;
141(20):8327-8338.
PMID: 31042030
For HIV to become infectious, any new virion produced from an infected cell must undergo a maturation process that involves the assembly of viral polyproteins Gag and Gag-Pol at the...
4.
Barsov E, Trivett M, Minang J, Sun H, Ohlen C, Ott D
PLoS One
. 2018 Mar;
13(3):e0195246.
PMID: 29590210
[This corrects the article DOI: 10.1371/journal.pone.0023703.].
5.
Fennessey C, Pinkevych M, Immonen T, Reynaldi A, Venturi V, Nadella P, et al.
PLoS Pathog
. 2017 May;
13(5):e1006359.
PMID: 28472156
HIV and SIV infection dynamics are commonly investigated by measuring plasma viral loads. However, this total viral load value represents the sum of many individual infection events, which are difficult...
6.
Ayala V, Deleage C, Trivett M, Jain S, Coren L, Breed M, et al.
J Virol
. 2017 Mar;
91(11).
PMID: 28298605
Follicular helper CD4 T cells, T, residing in B-cell follicles within secondary lymphoid tissues, are readily infected by AIDS viruses and are a major source of persistent virus despite relative...
7.
Ayala V, Trivett M, Barsov E, Jain S, Piatak Jr M, Trubey C, et al.
J Virol
. 2016 Aug;
90(21):9942-9952.
PMID: 27558423
Importance: The establishment of AIDS virus infection in an individual is essentially a race between the spreading virus and host immune defenses. Cell-mediated immune responses induced by infection or vaccination...
8.
Ayala V, Trivett M, Coren L, Jain S, Bohn P, Wiseman R, et al.
Virology
. 2016 Mar;
493:100-12.
PMID: 27017056
To study CD4(+)T-cell suppression of AIDS virus replication, we isolated nine rhesus macaque SIVGag-specific CD4(+)T-cell clones. One responding clone, Gag68, produced a typical cytotoxic CD8(+)T-cell response: induction of intracellular IFN-γ,...
9.
Coren L, Trivett M, Jain S, Ayala V, Del Prete G, Ohlen C, et al.
Retrovirology
. 2015 Mar;
12:11.
PMID: 25809491
Background: The TRIM5α protein is a principal restriction factor that contributes to an HIV-1 replication block in rhesus macaque CD4+ T cells by preventing reverse transcription. HIV-1 restriction is induced...
10.
Coren L, Jain S, Trivett M, Ohlen C, Ott D
Biotechniques
. 2015 Mar;
58(3):135-9.
PMID: 25757546
Here we present an improved strategy for producing T-cell receptor (TCR)-expressing retroviral vectors using a Golden Gate cloning strategy. This method takes advantage of the modular nature of TCR genes...