David Deamer
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Explore the profile of David Deamer including associated specialties, affiliations and a list of published articles.
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51
Citations
1641
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Recent Articles
1.
Song X, Simonis P, Deamer D, Zare R
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2412784121.
PMID: 39585974
The key first step in the oligomerization of monomers is to find an initiator, which is usually done by thermolysis or photolysis. We present a markedly different approach that initiates...
2.
Deamer D
J Mol Evol
. 2024 Sep;
92(5):530-538.
PMID: 39230713
The path to minimal life involves a series of stages that can be understood in terms of incremental, stepwise additions of complexity ranging from simple solutions of organic compounds to...
3.
Da Silva L, Eiby S, Bjerrum M, Thulstrup P, Deamer D, Hassenkam T
Biochem Biophys Res Commun
. 2024 Apr;
712-713:149938.
PMID: 38640739
Polymerization of nucleotides under prebiotic conditions simulating the early Earth has been extensively studied. Several independent methods have been used to verify that RNA-like polymers can be produced by hot...
4.
Paula S, Acosta A, Judge N, Ramirez S, Sandhu A, Deamer D
Biosystems
. 2024 Mar;
238:105189.
PMID: 38479655
A frequently debated topic related to the origin of life centers around the question of how complex forms of life on today's Earth may have evolved over time from simpler...
5.
Ross D, Deamer D
Life (Basel)
. 2023 Aug;
13(8).
PMID: 37629605
The commonly supposed template-based format for RNA self-replication requires both duplex assembly and disassembly. This requisite binary provision presents a challenge to the development of a serviceable self-replication model since...
6.
Deamer D
Life (Basel)
. 2022 Sep;
12(9).
PMID: 36143465
Most experimental results that guide research related to the origin of life are from laboratory simulations of the early Earth conditions. In the laboratory, emphasis is placed on the purity...
7.
Hassenkam T, Deamer D
Sci Rep
. 2022 Jun;
12(1):10098.
PMID: 35739144
It is possible that the transition from abiotic systems to life relied on RNA polymers that served as ribozyme-like catalysts and for storing genetic information. The source of such polymers...
8.
Deamer D, Cary F, Damer B
Astrobiology
. 2022 Jun;
22(7):889-900.
PMID: 35675644
The concept of habitability is now widely used to describe zones in a solar system in which planets with liquid water can sustain life. Because habitability does not explicitly incorporate...
9.
Ross D, Deamer D
Astrobiology
. 2022 Feb;
22(2):192-196.
PMID: 35157512
The roots of biological homochirality remain unknown despite decades of study. A commonly proposed path includes an initial small enantiomeric excess that was amplified over time, but a satisfactory source...
10.
Deamer D
Life (Basel)
. 2021 Feb;
11(2).
PMID: 33578711
Publications related to the origin of life are mostly products of laboratory research and have the tacit assumption that the same reactions would have been possible on the early Earth...