David D M Nicholl
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Explore the profile of David D M Nicholl including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
266
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Recent Articles
1.
Nicholl D, Hanly P, MacRae J, Zalucky A, Handley G, Sola D, et al.
Physiol Rep
. 2023 Apr;
11(8):e15677.
PMID: 37078461
Obstructive sleep apnea (OSA) is common in heart and kidney disease, both conditions prone to fluid retention. Nocturnal rostral fluid shift contributes to the pathogenesis of OSA in men more...
2.
Nicholl D, Whitelaw J, Weir R, Bissonnette M, Gill J, Landsberg D
Transplant Direct
. 2021 Nov;
7(12):e790.
PMID: 34805492
No abstract available.
3.
Sherwood K, Nicholl D, Fenninger F, Wu V, Wong P, Benedicto V, et al.
Front Immunol
. 2021 Oct;
12:753558.
PMID: 34630432
To date there is limited data on the immune profile and outcomes of solid organ transplant recipients who encounter COVID-19 infection early post-transplant. Here we present a unique case where...
4.
Nicholl D, Hanly P, Zalucky A, Handley G, Sola D, Ahmed S
Sleep
. 2021 Mar;
44(5).
PMID: 33734385
Study Objectives: Nocturnal hypoxemia (NH) in obstructive sleep apnea (OSA) is associated with renal renin-angiotensin-aldosterone system (RAAS) up-regulation and loss of kidney function. Continuous positive airway pressure (CPAP) therapy is...
5.
Nicholl D, Hanly P, Zalucky A, Handley G, Sola D, Ahmed S
Am J Physiol Renal Physiol
. 2019 Oct;
318(1):F25-F34.
PMID: 31608672
Men have faster loss of kidney function and greater renal renin-angiotensin system (RAS) activity compared with women. Obstructive sleep apnea (OSA) is common in chronic kidney disease; the vascular effects...
6.
Nicholl D, Hanly P, Zalucky A, Mann M, MacRae J, Poulin M, et al.
J Clin Sleep Med
. 2018 Sep;
14(9):1509-1520.
PMID: 30176965
Study Objectives: Obstructive sleep apnea (OSA) is associated with increased cardiovascular risk. The effect of OSA treatment with continuous positive airway pressure (CPAP) on the cardiovascular response to a stressor...
7.
Zalucky A, Nicholl D, Hanly P, Poulin M, Turin T, Walji S, et al.
Am J Respir Crit Care Med
. 2015 Jun;
192(7):873-80.
PMID: 26102156
Rationale: Obstructive sleep apnea (OSA) and nocturnal hypoxemia are associated with chronic kidney disease and up-regulation of the renin-angiotensin system (RAS), which is deleterious to renal function. The extent to...
8.
Lee J, Turin T, Nicholl D, Ahmed S, Loewen A, Hemmelgarn B, et al.
Sleep Breath
. 2014 Nov;
19(2):669-75.
PMID: 25369789
Purpose: Obstructive sleep apnea (OSA) is common among patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Home sleep testing is used to diagnose OSA in many studies...
9.
Nicholl D, Hanly P, Poulin M, Handley G, Hemmelgarn B, Sola D, et al.
Am J Respir Crit Care Med
. 2014 Jul;
190(5):572-80.
PMID: 25033250
Rationale: Obstructive sleep apnea (OSA) has been associated with kidney function loss, which may be related to changes in the renin-angiotensin system (RAS). Objectives: We sought to determine the effect...
10.
Beaudin A, Pun M, Yang C, Nicholl D, Steinback C, Slater D, et al.
J Am Heart Assoc
. 2014 May;
3(3):e000875.
PMID: 24815497
Background: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular and cerebrovascular disease resulting from intermittent hypoxia (IH)-induced inflammation. Cyclooxygenase (COX)-formed prostanoids mediate the inflammatory response, and regulate...