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David Christmas

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Articles 21
Citations 420
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Recent Articles
1.
Langan Martin J, Strawbridge R, Christmas D, Fleming M, Kelly S, Varveris D, et al.
Biol Psychiatry Glob Open Sci . 2025 Feb; 5(2):100434. PMID: 39926701
Background: Electroconvulsive therapy (ECT) is an effective treatment option for several psychiatric disorders, including treatment-resistant depression, but there are concerns about potential adverse effects, particularly on cognition. This study describes...
2.
Hook R, Isobe M, Savulich G, Grant J, Ioannidis K, Christmas D, et al.
Eur Neuropsychopharmacol . 2023 Mar; 71:55-64. PMID: 36989539
The role of the adenosine neurochemical system in human cognition is under-studied, despite such receptors being distributed throughout the brain. The aim of this study was to shed light on...
3.
Munchenberg P, Joyce E, Matthews K, Christmas D, Zrinzo L
Brain Sci . 2022 Oct; 12(10). PMID: 36291313
(1) Background: Major depressive disorder (MDD) generates a large proportion of global disease burden. Stereotactic radiofrequency ablation (SRA) may be beneficial for selected patients with its most debilitating and refractory...
4.
Scholz V, Hook R, Rostami Kandroodi M, Algermissen J, Ioannidis K, Christmas D, et al.
Neuropsychopharmacology . 2022 Mar; 47(8):1503-1512. PMID: 35260787
Motivations shape our behaviour: the promise of reward invigorates, while in the face of punishment, we hold back. Abnormalities of motivational processing are implicated in clinical disorders characterised by excessive...
5.
Burrin C, Daniels N, Cardinal R, Hayhurst C, Christmas D, Zimbron J
Case Rep Psychiatry . 2021 Jun; 2021:6615723. PMID: 34136300
Attempted suicide and deliberate self-harm are common and challenging presentations in the emergency department. A proportion of these patients refuse interventions and this presents the clinical, legal, and ethical dilemma...
6.
Tolomeo S, Christmas D, Jentzsch I, Johnston B, Sprengelmeyer R, Matthews K, et al.
Brain . 2016 May; 139(Pt 6):1844-54. PMID: 27190027
Converging evidence has linked the anterior mid-cingulate cortex to negative affect, pain and cognitive control. It has previously been proposed that this region uses information about punishment to control aversively...
7.
Christmas D, Matthews K
Stereotact Funct Neurosurg . 2015 Dec; 93(6):387-92. PMID: 26671577
Background: The evidence base to guide therapeutic choices for patients with chronic and treatment-refractory depression (TRD) remains weak. There is limited comparative information available to guide the choice of intervention...
8.
Johnston B, Douglas Steele J, Tolomeo S, Christmas D, Matthews K
PLoS One . 2015 Jul; 10(7):e0132958. PMID: 26186455
The application of machine learning techniques to psychiatric neuroimaging offers the possibility to identify robust, reliable and objective disease biomarkers both within and between contemporary syndromal diagnoses that could guide...
9.
Johnston B, Tolomeo S, Gradin V, Christmas D, Matthews K, Douglas Steele J
Brain . 2015 Jul; 138(Pt 9):2766-76. PMID: 26133661
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies...
10.
Christmas D, Diaper A, Wilson S, Rich A, Phillips S, Udo de Haes J, et al.
Hum Psychopharmacol . 2014 Jan; 29(2):163-71. PMID: 24424780
Objective: Cognitive impairment is integral to many neurological illnesses. Specific enhancement of glutamatergic transmission may improve memory and learning. Org 25935 increases the synaptic availability of glycine, an obligate co-agonist...