David C Poole
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Explore the profile of David C Poole including associated specialties, affiliations and a list of published articles.
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264
Citations
4975
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Recent Articles
1.
Weber R, Schulze K, Kenney N, Scheuermann B, Kunkel O, Ade C, et al.
Am J Cancer Res
. 2025 Mar;
15(2):487-500.
PMID: 40084375
Breast cancer patients' maximal O uptake (V̇Omax) values average 60-80% of age-predicted values which is often attributed to adjuvant therapy rather than risk factors, comorbidities, or the tumor and associated...
2.
Horn A, White Z, Hall S, Morrison K, Schulze K, Muller-Delp J, et al.
J Physiol
. 2025 Mar;
603(6):1439-1459.
PMID: 40023797
Diaphragm hyperaemia and regional blood flow distribution are impaired with ageing, potentially consequent to altered vascular structure and/or diminished vasomotor function. Evidence from locomotory skeletal muscle suggests that age-related diaphragm...
3.
Burnley M, Vanhatalo A, Poole D, Jones A
J Physiol
. 2025 Feb;
603(6):1361-1374.
PMID: 39988844
One hundred years ago, A.V. Hill authored three manuscripts analysing athletic world records from a physiological perspective. That analysis, grounded in Hill's understanding of contemporary muscle bioenergetics, provides a fascinating...
4.
Schulze K, Horn A, Weber R, Hageman K, Scheuermann B, Ade C, et al.
Respir Physiol Neurobiol
. 2025 Feb;
335:104414.
PMID: 39971146
Pulmonary hypertension (PH) is a disease characterized by increased pulmonary arterial pressures, impaired gas exchange, dyspnea, and diaphragmatic dysfunction. Specifically, in PH, the diaphragm displays impaired contractility, vascular dysfunction, and...
5.
Zamani P, Shah S, Cohen J, Zhao M, Yang W, Afable J, et al.
JAMA Cardiol
. 2024 Dec;
10(3):284-289.
PMID: 39693096
Importance: Nitric oxide deficiency may contribute to exercise intolerance in patients with heart failure with preserved ejection fraction (HFpEF). Prior pilot studies have shown improvements in exercise tolerance with single-dose...
6.
Schulze K, Weber R, Horn A, Hageman K, Kenney N, Behnke B, et al.
J Physiol
. 2024 Dec;
603(2):337-351.
PMID: 39625445
Pulmonary hypertension (PH) is a chronic, progressive disease characterized by pulmonary vascular remodelling, dyspnoea and exercise intolerance. Key facets of dyspnoea and exercise intolerance include skeletal and respiratory muscle contractile...
7.
Tabuchi A, Kikuchi Y, Takagi R, Tanaka Y, Hoshino D, Poole D, et al.
J Appl Physiol (1985)
. 2024 Nov;
138(1):1-12.
PMID: 39546386
Eccentric contractions (ECC) are accompanied by the accumulation of intracellular calcium ions ([Ca]) and induce skeletal muscle damage. Suppressed muscle damage in repeated bouts of ECC is well characterized; however,...
8.
9.
Tabuchi A, Poole D, Kano Y
Exerc Sport Sci Rev
. 2024 Sep;
53(1):23-30.
PMID: 39262047
Eccentric contractions (ECC) induce excessive intracellular calcium ion (Ca 2+ ) accumulation and muscle structural damage in localized regions of the muscle fibers. In this investigation, we present the novel...
10.
Caen K, Poole D, Vanhatalo A, Jones A
Sports Med
. 2024 Aug;
54(10):2497-2513.
PMID: 39196486
From a physiological perspective, the delineation between steady-state and non-steady-state exercise, also referred to as the maximal metabolic steady state, holds paramount importance for evaluating athletic performance and designing and...