David C LaFon
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Explore the profile of David C LaFon including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
98
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Recent Articles
1.
LaFon D, Helgeson E, Lindberg S, Voelker H, Bhatt S, Casaburi R, et al.
JAMA Netw Open
. 2024 May;
7(5):e247535.
PMID: 38771577
Importance: While β-blockers are associated with decreased mortality in cardiovascular disease (CVD), exacerbation-prone patients with chronic obstructive pulmonary disease (COPD) who received metoprolol in the Beta-Blockers for the Prevention of...
2.
LaFon D, Dransfield M
Am J Respir Crit Care Med
. 2024 Mar;
210(1):20-21.
PMID: 38452226
No abstract available.
3.
Opron K, Begley L, Erb-Downward J, Li G, Alexis N, Barjaktarevic I, et al.
Am J Respir Crit Care Med
. 2024 Jan;
210(2):186-200.
PMID: 38261629
The airway microbiome has the potential to shape chronic obstructive pulmonary disease (COPD) pathogenesis, but its relationship to outcomes in milder disease is unestablished. To identify sputum microbiome characteristics associated...
4.
Ravichandran S, Erra-Diaz F, Karakaslar O, Marches R, Kenyon-Pesce L, Rossi R, et al.
Nat Immunol
. 2024 Jan;
25(2):316-329.
PMID: 38182669
Pneumococcal infections cause serious illness and death among older adults. The capsular polysaccharide vaccine PPSV23 and conjugated alternative PCV13 can prevent these infections; yet, underlying immunological responses and baseline predictors...
5.
LaFon D, Woo H, Fedarko N, Azar A, Hill H, Tebo A, et al.
Clin Immunol
. 2023 Apr;
250:109324.
PMID: 37030524
While hypogammaglobulinemia is associated with COPD exacerbations, it is unknown whether frequent exacerbators have specific defects in antibody production/function. We hypothesized that reduced quantity/function of serum pneumococcal antibodies correlate with...
6.
LaFon D, Thiel S, Kim Y, Dransfield M, Nahm M
Immun Ageing
. 2020 Jun;
17:18.
PMID: 32536956
Background: There is increasing recognition of the significance of chronic, low-level inflammation in older adults, or "inflammaging." Innate immune responses and host-bacterial interactions are recognized as key factors in inflammaging....
7.
Leitao Filho F, Mattman A, Schellenberg R, Criner G, Woodruff P, Lazarus S, et al.
Chest
. 2020 May;
158(4):1420-1430.
PMID: 32439504
Background: Hypogammaglobulinemia (serum IgG levels < 7.0 g/L) has been associated with increased risk of COPD exacerbations but has not yet been shown to predict hospitalizations. Research Question: To determine...
8.
Sterrett S, Peng B, Burton R, LaFon D, Westfall A, Singh S, et al.
Vaccine
. 2020 Jan;
38(7):1778-1786.
PMID: 31911030
Background: PCV13 (conjugated polysaccharide) and PPSV23 (polysaccharide only) are two licensed vaccines targeting S. pneumoniae. The role of CD4 T-cell responses in pneumococcal vaccines among healthy participants and their impact...
9.
LaFon D, Bhatt S, Labaki W, Rahaghi F, Moll M, Bowler R, et al.
Eur Respir J
. 2019 Nov;
55(2).
PMID: 31772001
No abstract available.
10.
LaFon D, Nahm M
Transfusion
. 2018 Dec;
58 Suppl 3:3114-3120.
PMID: 30536435
Background: Immunoglobulin replacement therapy is a cornerstone of the treatment of primary immunodeficiencies. Preparations used for replacement therapy are processed by purifying immunoglobulins from large pools of plasma, which were...