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David Battaglia

Explore the profile of David Battaglia including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 1206
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Recent Articles
1.
Liang D, Mikhalchenko A, Ma H, Marti Gutierrez N, Chen T, Lee Y, et al.
Nat Commun . 2023 Mar; 14(1):1219. PMID: 36882397
Range of DNA repair in response to double-strand breaks induced in human preimplantation embryos remains uncertain due to the complexity of analyzing single- or few-cell samples. Sequencing of such minute...
2.
Marti Gutierrez N, Mikhalchenko A, Ma H, Koski A, Li Y, Van Dyken C, et al.
iScience . 2022 Mar; 25(3):103901. PMID: 35243258
Cells transmit their genomes vertically to daughter cells during cell divisions. Here, we demonstrate the occurrence and extent of horizontal mitochondrial (mt)DNA acquisition between cells that are not in a...
3.
Metcalf E, Masterson K, Battaglia D, Thompson J, Foss R, Beck R, et al.
Reprod Fertil Dev . 2020 Jul; 32(11):1012-1021. PMID: 32693913
Optimising the developmental potential of immature equine oocytes and invitro-produced (IVP) embryos was explored through modifications of established media and holding temperature. In Experiment 1, delaying spontaneous resumption of meiosis...
4.
Cook N, Masterson K, Battaglia D, Beck R, Metcalf E
Reprod Fertil Dev . 2020 Mar; 32(3):253-258. PMID: 32172784
Numerous variables affect invitro blastocyst development following intracytoplasmic sperm injection (ICSI). The paternal factor is affected by initial semen quality, processing techniques and final selection of individual spermatozoon for injection....
5.
Brooks K, Daughtry B, Metcalf E, Masterson K, Battaglia D, Gao L, et al.
Reprod Fertil Dev . 2019 Nov; 31(12):1840-1850. PMID: 31759400
The timing of early mitotic events during preimplantation embryo development is important for subsequent embryogenesis in many mammalian species, including mouse and human, but, to date, no study has closely...
6.
Kang E, Wu J, Marti Gutierrez N, Koski A, Tippner-Hedges R, Agaronyan K, et al.
Nature . 2019 Mar; 567(7747):E5-E9. PMID: 30814738
Change history In this Letter, there are several errors regarding the assignments of mtDNA haplotypes for a subset of egg donors from our study. These errors have not been corrected...
7.
Ma H, Marti-Gutierrez N, Park S, Wu J, Hayama T, Darby H, et al.
Nature . 2018 Aug; 560(7717):E10-E23. PMID: 30089923
No abstract available.
8.
Ma H, Marti-Gutierrez N, Park S, Wu J, Lee Y, Suzuki K, et al.
Nature . 2017 Aug; 548(7668):413-419. PMID: 28783728
Genome editing has potential for the targeted correction of germline mutations. Here we describe the correction of the heterozygous MYBPC3 mutation in human preimplantation embryos with precise CRISPR-Cas9-based targeting accuracy...
9.
Kang E, Wu J, Marti Gutierrez N, Koski A, Tippner-Hedges R, Agaronyan K, et al.
Nature . 2016 Dec; 540(7632):270-275. PMID: 27919073
Maternally inherited mitochondrial (mt)DNA mutations can cause fatal or severely debilitating syndromes in children, with disease severity dependent on the specific gene mutation and the ratio of mutant to wild-type...
10.
Ma H, ONeil R, Marti Gutierrez N, Hariharan M, Zhang Z, He Y, et al.
Cell Stem Cell . 2016 Nov; 20(1):112-119. PMID: 27840020
Oocyte defects lie at the heart of some forms of infertility and could potentially be addressed therapeutically by alternative routes for oocyte formation. Here, we describe the generation of functional...