David B Sattelle
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Explore the profile of David B Sattelle including associated specialties, affiliations and a list of published articles.
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123
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4096
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Recent Articles
1.
Ito R, Ojima H, Takebayashi M, Takeuchi M, Takahashi H, Mori S, et al.
Pestic Biochem Physiol
. 2025 Mar;
209:106325.
PMID: 40082022
TMX3 is essential for the functional expression of insect nicotinic acetylcholine receptors (nAChRs) and RIC-3 and UNC-50 modulate it. In addition to these cofactors, NACHO has been shown to enhance...
2.
Takebayashi M, Mori S, Ito R, Takayama K, Ojima H, Takeuchi M, et al.
Pest Manag Sci
. 2024 Aug;
PMID: 39167025
A transmembrane thioredoxin (TMX3) enables the functional expression of insect nicotinic acetylcholine receptors (nAChRs) in Xenopus laevis oocytes, while co-factors RIC-3 and UNC-50 regulate the receptor expression level. RIC-3 (resistant...
3.
Ito R, Kamiya M, Takayama K, Mori S, Matsumoto R, Takebayashi M, et al.
Open Biol
. 2024 Jul;
14(7):240057.
PMID: 39043224
With the spread of resistance to long-established insecticides targeting malaria vectors, understanding the actions of compounds newly identified for vector control is essential. With new commercial vector-control products containing neonicotinoids...
4.
Poulton B, Colman F, Anthousi A, Sattelle D, Lycett G
PLoS Negl Trop Dis
. 2024 Feb;
18(2):e0011595.
PMID: 38377131
Insecticide resistance is a serious threat to our ability to control mosquito vectors which transmit pathogens including malaria parasites and arboviruses. Understanding the underlying mechanisms is an essential first step...
5.
Coghlan A, Partridge F, Duque-Correa M, Rinaldi G, Clare S, Seymour L, et al.
PLoS Negl Trop Dis
. 2023 Sep;
17(9):e0011205.
PMID: 37669291
Hundreds of millions of people worldwide are infected with the whipworm Trichuris trichiura. Novel treatments are urgently needed as current drugs, such as albendazole, have relatively low efficacy. We have...
6.
Koizumi W, Otsubo S, Furutani S, Niki K, Takayama K, Fujimura S, et al.
Mol Pharmacol
. 2023 Mar;
103(6):299-310.
PMID: 36948535
The anthelmintic paraherquamide A acts selectively on the nematode L-type nicotinic acetylcholine receptors (nAChRs), but the mechanism of its selectivity is unknown. This study targeted the basis of paraherquamide A...
7.
Komori Y, Takayama K, Okamoto N, Kamiya M, Koizumi W, Ihara M, et al.
PLoS Genet
. 2023 Feb;
19(2):e1010522.
PMID: 36795653
Neonicotinoid insecticides target insect nicotinic acetylcholine receptors (nAChRs) and their adverse effects on non-target insects are of serious concern. We recently found that cofactor TMX3 enables robust functional expression of...
8.
Sattelle D
Pestic Biochem Physiol
. 2022 Sep;
187:105175.
PMID: 36127074
Insect-borne diseases of humans, animals and plants can be devastating. The direct damage to crops by insect and nematode pests can also severely reduce crop yields and threaten harvests. Parasitic...
9.
Partridge F, Poulton B, Lake M, Lees R, Mann H, Lycett G, et al.
Molecules
. 2021 Oct;
26(20).
PMID: 34684807
Mosquito-borne viruses including dengue, Zika, and Chikungunya viruses, and parasites such as malaria and endanger health and economic security around the globe, and emerging mosquito-borne pathogens have pandemic potential. However,...
10.
Buckingham S, Partridge F, Poulton B, Miller B, McKendry R, Lycett G, et al.
PLoS Negl Trop Dis
. 2021 Jun;
15(6):e0008639.
PMID: 34081710
Pyrethroid-impregnated nets have contributed significantly to halving the burden of malaria but resistance threatens their future efficacy and the pipeline of new insecticides is short. Here we report that an...