David A Calhoun
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Explore the profile of David A Calhoun including associated specialties, affiliations and a list of published articles.
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188
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5868
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Recent Articles
1.
Girard A, Denney T, Gupta H, DellItalia L, Calhoun D, Oparil S, et al.
Int J Cardiovasc Imaging
. 2023 Dec;
40(3):487-497.
PMID: 38123867
To determine the blood pressure independent effects of spironolactone on left atrial (LA) size and function in patients with resistant hypertension (RHTN). Patients with RHTN (n = 36, mean age...
2.
Matanes F, Siddiqui M, Velasco A, Sharifov O, Kreps E, Dudenbostel T, et al.
J Clin Hypertens (Greenwich)
. 2023 Apr;
25(5):416-425.
PMID: 37013369
Resistant hypertension (RHTN), defined as blood pressure (BP) that is uncontrolled with ≥3 medications, including a long-acting thiazide diuretic, also includes a subset with BP that is controlled with ≥4...
3.
Butts B, Brown J, Denney Jr T, Ballinger S, Lloyd S, Oparil S, et al.
Hypertension
. 2022 Feb;
79(4):775-784.
PMID: 35164526
Background: We previously reported increased plasma XO (xanthine oxidase) activity in patients with resistant hypertension. Increased XO can cause mitochondrial DNA damage and promote release of fragments called mitochondrial DNA...
4.
Gamble F, Aufan M, Sharifov O, Williams L, Reighard S, Calhoun D, et al.
Physiol Meas
. 2022 Jan;
43(2).
PMID: 35073533
We developed a method using cardiovascular magnetic resonance imaging to model the untwisting of the left ventricle (LV) as a damped torsional harmonic oscillator to estimate shear modulus (intrinsic myocardial...
5.
Kwon Y, Baruch M, Stafford P, Bonner H, Cho Y, Mazimba S, et al.
J Hypertens
. 2021 Nov;
40(3):520-527.
PMID: 34751170
Background: Obstructive sleep apnoea (OSA) episode related blood pressure (BP) surge may mediate the association of OSA with cardiovascular disease. However, BP is not measured during a clinical sleep study....
6.
Aryal S, Siddiqui M, Sharifov O, Coffin M, Zhang B, Gaddam K, et al.
J Am Heart Assoc
. 2021 Aug;
10(17):e019434.
PMID: 34459249
Background Aortic stiffness is an independent predictor of cardiovascular events in patients with arterial hypertension. Resistant hypertension is often linked to hyperaldosteronism and associated with adverse outcomes. Spironolactone, a mineralocorticoid...
7.
Santillan M, Becker R, Calhoun D, Cowley A, Flynn J, Grobe J, et al.
Hypertension
. 2021 May;
77(6):1857-1866.
PMID: 33934625
In 2015, the American Heart Association awarded 4-year funding for a Strategically Focused Research Network focused on hypertension composed of 4 Centers: Cincinnati Children's Hospital, Medical College of Wisconsin, University...
8.
Gaffo A, Calhoun D, Rahn E, Oparil S, Li P, Dudenbostel T, et al.
Arthritis Rheumatol
. 2021 Mar;
73(8):1514-1522.
PMID: 33779064
Objective: To determine whether serum urate reduction with allopurinol lowers blood pressure (BP) in young adults and the mechanisms mediating this hypothesized effect. Methods: We conducted a single-center, randomized, double-blind,...
9.
Dudenbostel T, Li P, Calhoun D
Am J Hypertens
. 2020 Dec;
34(6):600-608.
PMID: 33290515
Background: Having previously reported that aldosterone levels increase progressively with body mass index (BMI), the current analysis was done to determine to what extent this association is related to dietary...
10.
Siddiqui M, Judd E, Zhang B, Dudenbostel T, Carey R, Oparil S, et al.
Hypertension
. 2020 Dec;
77(2):435-444.
PMID: 33280407
Masked uncontrolled hypertension (MUCH) in treated patients is defined as controlled office blood pressure (BP) but uncontrolled out-of-clinic ambulatory BP. Previously, we have shown that patients with MUCH have evidence...