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David A Barnett

Explore the profile of David A Barnett including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 302
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Recent Articles
1.
Murphy E, Joy A, Ouellette R, Barnett D
Anal Sci Adv . 2024 May; 2(5-6):299-307. PMID: 38716156
Peptide and protein quantitation by liquid chromatography-mass spectrometry relies on the assumption of linear signal response with concentration. At low concentrations, analyte adsorption to pipette tips, sample vials and equipment...
2.
Ayad A, Hebert M, Doiron J, Loucif-Ayad W, Daas T, Smagghe G, et al.
Chem Biodivers . 2024 Jan; 21(4):e202301758. PMID: 38241641
Propolis was collected from honeybee hives in three geographically distinct Algerian climates and extracts were characterized for composition and bioactivity. Bees were identified as native subspecies using an in-silico DraI...
3.
Hebert M, Selka A, Lebel A, Doiron J, Chiasson A, Gauvin V, et al.
Int Immunopharmacol . 2023 Jun; 121:110419. PMID: 37295028
The inflammatory response is an essential process for the host defence against pathogens. Lipid mediators are important in coordinating the pro-inflammatory and pro-resolution phases of the inflammatory process. However, unregulated...
4.
Johnson M, Nowlan S, Sahin G, Barnett D, Joy A, Touaibia M, et al.
Front Oncol . 2022 Feb; 12:841054. PMID: 35223522
Kidney cancer is one of the top ten cancer diagnosed worldwide and its incidence has increased the last 20 years. Clear Cell Renal Cell Carcinoma (ccRCC) are characterized by mutations...
5.
Kumar A, Dhadi S, Mai N, Taylor C, Roy J, Barnett D, et al.
J Extracell Vesicles . 2021 Sep; 10(11):e12138. PMID: 34478244
Several studies have demonstrated the potential uses of extracellular vesicles (EVs) for liquid biopsy-based diagnostic tests and therapeutic applications; however, clinical use of EVs presents a challenge as many currently-available...
6.
Roy J, Taylor C, Beauregard A, Dhadi S, Ayre D, Fry S, et al.
Sci Rep . 2021 Apr; 11(1):8085. PMID: 33850235
Extracellular vesicles (EVs) have been recognized as a rich material for the analysis of DNA, RNA, and protein biomarkers. A remaining challenge for the deployment of EV-based diagnostic and prognostic...
7.
Murphy E, Joy A, Ouellette R, Barnett D
Anal Biochem . 2021 Feb; 619:114137. PMID: 33582115
Several common reagents for the alkylation of cysteine residues of model intact proteins were evaluated for reaction speed, yield of alkylated product and degree of over-alkylation using an online LC-MS...
8.
Bullerwell C, Robichaud P, Deprez P, Joy A, Wajnberg G, DSouza D, et al.
Sci Rep . 2021 Jan; 11(1):1537. PMID: 33452395
PAX5 and EBF1 work synergistically to regulate genes that are involved in B lymphocyte differentiation. We used the KIS-1 diffuse large B cell lymphoma cell line, which is reported to...
9.
Sambou M, Jean-Francois J, Moutombi F, Doiron J, Hebert M, Joy A, et al.
Molecules . 2020 May; 25(10). PMID: 32455632
Soxhlet (SE), microwave-assisted (MAE) and ultrasound-assisted (UAE) extraction were compared using ten extraction solvents for their efficiency to extract phenolic and flavonoid antioxidants from Eastern Canada propolis. Extracts were compared...
10.
Mbarik M, Poirier S, Doiron J, Selka A, Barnett D, Cormier M, et al.
Pharmacol Res Perspect . 2019 Sep; 7(5):e00524. PMID: 31523435
5-lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, potent lipid mediators involved in inflammatory diseases, and both 5-LO and the leukotrienes are validated therapeutic targets. Caffeic acid phenethyl ester (CAPE) is...