Dave Chapman
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Explore the profile of Dave Chapman including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
495
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Recent Articles
1.
Chapman D, Poirier V, Fitzgerald K, Nicholson B, Hamilton W
Br J Gen Pract
. 2021 Jun;
71(712):e846-e853.
PMID: 34097639
Background: Although less common cancers account for almost half of all cancer diagnoses in England, their relative scarcity and complex presentation, often with non-specific symptoms, means that patients often experience...
2.
Sanchez-Cordon P, Jabbar T, Chapman D, Dixon L, Montoya M
J Virol
. 2020 May;
94(14).
PMID: 32376618
Following short immunization protocols, naturally attenuated African swine fever virus (ASFV) isolate OURT88/3 and deletion mutant BeninΔMGF have previously been shown to induce high percentages of protection in domestic pigs...
3.
Montaner-Tarbes S, Pujol M, Jabbar T, Hawes P, Chapman D, Portillo H, et al.
Viruses
. 2019 Sep;
11(10).
PMID: 31547130
African swine fever is a devastating hemorrhagic infectious disease, which affects domestic and wild swines () of all breeds and ages, with a high lethality of up to 90-100% in...
4.
Munck Af Rosenschold M, Johannesson P, Nikitidis A, Tyrchan C, Chang H, Ronn R, et al.
J Med Chem
. 2019 Aug;
62(17):7769-7787.
PMID: 31415176
While bronchodilators and inhaled corticosteroids are the mainstay of asthma treatment, up to 50% of asthmatics remain uncontrolled. Many studies show that the cysteinyl leukotriene cascade remains highly activated in...
5.
Ripa L, Edman K, Dearman M, Edenro G, Hendrickx R, Ullah V, et al.
J Med Chem
. 2018 Feb;
61(5):1785-1799.
PMID: 29424542
Synthetic glucocorticoids (GC) are essential for the treatment of a broad range of inflammatory diseases. However, their use is limited by target related adverse effects on, e.g., glucose homeostasis and...
6.
Jancovich J, Chapman D, Hansen D, Robida M, Loskutov A, Craciunescu F, et al.
J Virol
. 2018 Feb;
92(8).
PMID: 29386289
African swine fever virus (ASFV) causes an acute hemorrhagic fever in domestic pigs, with high socioeconomic impact. No vaccine is available, limiting options for control. Although live attenuated ASFV can...
7.
Sanchez-Cordon P, Jabbar T, Berrezaie M, Chapman D, Reis A, Sastre P, et al.
Vaccine
. 2017 Dec;
36(5):707-715.
PMID: 29254837
A live attenuated African swine fever virus (ASFV) vaccine candidate, produced by deletion of several genes belonging to multi-gene families MGF360 and 505 from virulent Benin 97/1 strain (BeninΔMGF), induces...
8.
Sanchez-Cordon P, Chapman D, Jabbar T, Reis A, Goatley L, Netherton C, et al.
Antiviral Res
. 2016 Dec;
138:1-8.
PMID: 27908827
This study compares different combinations of doses and routes of immunisation of pigs with low virulent African swine fever virus (ASFV) genotype I isolate OURT88/3, including the intramuscular and intranasal...
9.
Lithgow P, Takamatsu H, Werling D, Dixon L, Chapman D
Vet Microbiol
. 2014 Jan;
168(2-4):413-9.
PMID: 24398227
The expression of surface markers on African swine fever virus (ASFV) infected cells was evaluated to assess their involvement in infection. Previous findings indicated CD163 expression was correlated with ASFV...
10.
King K, Chapman D, Argilaguet J, Fishbourne E, Hutet E, Cariolet R, et al.
Vaccine
. 2011 May;
29(28):4593-600.
PMID: 21549789
African swine fever (ASF) is an acute haemorrhagic disease of domestic pigs for which there is currently no vaccine. We showed that experimental immunisation of pigs with the non-virulent OURT88/3...