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Darren P Casey

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Articles 109
Citations 1930
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Recent Articles
11.
Bock J, Hughes W, Ueda K, Feider A, Hanada S, Casey D
Physiol Rep . 2021 Mar; 9(5):e14764. PMID: 33660935
Microvascular endothelial dysfunction precipitates cardiovascular disease mortality in patients with type 2 diabetes mellitus (T2DM). However, the relationship between glycemic management and microvascular endothelial function of these patients remains ill...
12.
Casey D, Bock J
Am J Physiol Heart Circ Physiol . 2021 Jan; 320(3):H991-H998. PMID: 33449848
Aging causes deleterious changes in resting conduit artery shear patterns and reduced blood flow during exercise partially attributable to reduced nitric oxide (NO). Inorganic nitrate increases circulating NO bioavailability and...
13.
Iwamoto E, Sakamoto R, Tsuchida W, Yamazaki K, Kamoda T, Neki T, et al.
Am J Physiol Heart Circ Physiol . 2020 Dec; 320(2):H679-H689. PMID: 33306444
This study aimed to elucidate the effects of change in estrogen during the menstrual cycle and menopause on shear-mediated dilation of the internal carotid artery (ICA), a potential index of...
14.
Bock J, Hanson B, Asama T, Feider A, Hanada S, Aldrich A, et al.
J Appl Physiol (1985) . 2020 Nov; 130(1):87-95. PMID: 33211592
Patients with obstructive sleep apnea (OSA) have increased cardiovascular disease risk largely attributable to hypertension. Heightened peripheral chemoreflex sensitivity (i.e., exaggerated responsiveness to hypoxia) facilitates hypertension in these patients. Nitric...
15.
Giersch G, Charkoudian N, Pereira T, Edgell H, Freeberg K, Craighead D, et al.
J Appl Physiol (1985) . 2020 Nov; 129(5):1122-1135. PMID: 33197376
No abstract available.
16.
Hanson B, Joyner M, Casey D
J Appl Physiol (1985) . 2020 Oct; 130(1):206-214. PMID: 33119464
Rapid-onset vasodilation (ROV) in response to a single muscle contraction is attenuated with aging. Moreover, sex-related differences in muscle blood flow and vasodilation during dynamic exercise have been observed in...
17.
Ueda K, Janiczek D, Casey D
J Cardiothorac Vasc Anesth . 2020 Sep; 35(1):73-80. PMID: 32921603
Objectives: Patients chronically treated with angiotensin-converting enzyme inhibitors (ACEIs) may develop hypotension after induction of general anesthesia. A fraction of these patients are resistant to therapeutic doses of vasopressors, which...
18.
Bock J, Hughes W, Ueda K, Feider A, Hanada S, Kruse N, et al.
Am J Physiol Heart Circ Physiol . 2020 Aug; 319(4):H797-H807. PMID: 32822215
Patients with type 2 diabetes mellitus (T2DM) exhibit diminished exercise capacity likely attributable to reduced skeletal muscle blood flow (i.e., exercise hyperemia). A potential underlying mechanism of the impaired hyperemic...
19.
Iwamoto E, Hanson B, Bock J, Casey D
J Appl Physiol (1985) . 2020 Jul; 129(3):603-611. PMID: 32702263
Cyclic intermittent hypoxia (IH) increases cerebral blood velocity. This enhanced velocity augments the commensurate shear stimulus and may subsequently increase cerebrovascular endothelial function. This study aimed to examine the effects...
20.
Bock J, Iwamoto E, Horak J, Feider A, Hanada S, Casey D
Am J Physiol Regul Integr Comp Physiol . 2020 May; 319(1):R11-R18. PMID: 32401628
Consumption of a single, sugar-sweetened beverage (SSB) impairs vascular endothelial function. Regular aerobic exercise improves endothelium-dependent vasodilation; however, it is unknown whether these beneficial effects persist with frequent SSB consumption....