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Darius Armstrong-James

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Articles 89
Citations 3360
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Recent Articles
1.
Carter C, Torre I, Blackburn S, Nwankwo L, Semple T, Rawal B, et al.
J Allergy Clin Immunol Pract . 2025 Mar; PMID: 40088970
Background: Allergic bronchopulmonary aspergillosis (ABPA) is characterised by a severe hypersensitivity reaction to Aspergillus species. Current treatment relies on oral corticosteroids (OCS) and triazole antifungal therapy, but there is increasing...
2.
Bercusson A, Williams T, Simmonds N, Alton E, Griesenbach U, Shah A, et al.
PLoS Pathog . 2025 Feb; 21(2):e1012784. PMID: 39903773
Aspergillus fumigatus (Af) is a major mould pathogen found ubiquitously in the air. It commonly infects the airways of people with cystic fibrosis (CF) leading to Aspergillus bronchitis or allergic...
3.
Adlakha A, Williams T, Shou X, Reed A, Lenhard B, Armstrong-James D
iScience . 2025 Feb; 28(2):111535. PMID: 39898039
Invasive pulmonary aspergillosis is a lethal opportunistic fungal infection in transplant recipients receiving calcineurin inhibitors. We previously identified a role for the calcineurin pathway in innate immune responses to and...
4.
Pates K, Shang Z, Jabbar R, Armstrong-James D, Schelenz S, Periselneris J, et al.
J Fungi (Basel) . 2024 Nov; 10(11). PMID: 39590706
Fungal infections are increasingly prevalent; however, antifungal stewardship attracts little funding or attention. Previous studies have shown that knowledge of guidelines and scientific evidence regarding antifungals is poor, leading to...
5.
Fisher M, Burnett F, Chandler C, Gow N, Gurr S, Hart A, et al.
NPJ Antimicrob Resist . 2024 Nov; 2(1):36. PMID: 39524479
The emergence of fungal antimicrobial resistance-fAMR-is having a growing impact on human and animal health, and food security. This roadmap charts inter-related actions that will enhance our ability to mitigate...
6.
Sehgal I, Muthu V, Seidel D, Sprute R, Armstrong-James D, Asano K, et al.
Mycoses . 2024 Oct; 67(10):e13810. PMID: 39462638
Objectives: Allergic bronchopulmonary aspergillosis (ABPA) is a complex lung disease associated with significant morbidity. The ABPA Working Group (AWG) of the International Society for Human and Animal Mycology (ISHAM) revised...
7.
Kappel D, Gifford H, Brackin A, Abdolrasouli A, Eyre D, Jeffery K, et al.
NPJ Antimicrob Resist . 2024 Oct; 2(1):26. PMID: 39359891
is a globally emerged fungal pathogen causing nosocomial invasive infections. Here, we use cutting-edge genomic approaches to elucidate the temporal and geographic epidemiology of drug-resistant within the UK. We analysed...
8.
Chesshyre E, Warren F, Shore A, Davies J, Armstrong-James D, Warris A
J Fungi (Basel) . 2024 Sep; 10(9). PMID: 39330359
Observational studies indicate that colonization and allergic bronchopulmonary aspergillosis (ABPA) in people with cystic fibrosis (CF) are associated with poorer lung health and increased disease severity. We performed a longitudinal...
9.
Arendrup M, Armstrong-James D, Borman A, Denning D, Fisher M, Gorton R, et al.
Open Forum Infect Dis . 2024 Jul; 11(7):ofae372. PMID: 39045012
Fungal diseases represent a considerable global health concern, affecting >1 billion people annually. In response to this growing challenge, the World Health Organization introduced the pivotal fungal priority pathogens list...
10.
Chakraborty A, Alsharqi L, Kostrzewa M, Armstrong-James D, Larrouy-Maumus G
Mol Omics . 2024 Apr; 20(6):390-396. PMID: 38623711
Glycosyl-inositol-phospho-ceramides (GIPCs) or glycosylphosphatidylinositol-anchored fungal polysaccharides are major lipids in plant and fungal plasma membranes and play an important role in stress adaption. However, their analysis remains challenging due to...