Dario Livio Longo
Overview
Explore the profile of Dario Livio Longo including associated specialties, affiliations and a list of published articles.
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Articles
61
Citations
932
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Recent Articles
1.
Gammaraccio F, Villano D, Irrera P, Anemone A, Carella A, Corrado A, et al.
J Imaging
. 2024 Jul;
10(7).
PMID: 39057737
CEST-MRI is an emerging imaging technique suitable for various in vivo applications, including the quantification of tumor acidosis. Traditionally, CEST contrast is calculated by asymmetry analysis, but the presence of...
2.
Lorito N, Subbiani A, Smiriglia A, Bacci M, Bonechi F, Tronci L, et al.
EMBO Mol Med
. 2024 Jun;
16(7):1533-1559.
PMID: 38926633
Triple-negative breast cancer (TNBC) has limited therapeutic options, is highly metastatic and characterized by early recurrence. Lipid metabolism is generally deregulated in TNBC and might reveal vulnerabilities to be targeted...
3.
Jardim-Perassi B, Irrera P, Oluwatola O, Abrahams D, Estrella V, Ordway B, et al.
Biomedicines
. 2024 Feb;
12(2).
PMID: 38398062
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed...
4.
Dhakan C, Anemone A, Ventura V, Carella A, Corrado A, Pirotta E, et al.
Metabolites
. 2023 Nov;
13(11).
PMID: 37999256
Proton transporters play a key role in maintaining the acidic tumor microenvironment; hence, their inhibition has been proposed as a new therapeutic treatment, although few methods can accurately assess their...
5.
David R, Rybina A, Burel J, Heriche J, Audergon P, Boiten J, et al.
EMBO J
. 2023 Nov;
42(23):e115008.
PMID: 37964598
The main goals and challenges for the life science communities in the Open Science framework are to increase reuse and sustainability of data resources, software tools, and workflows, especially in...
6.
Patrucco D, Cutrin J, Longo D, Botto E, Cong L, Aime S, et al.
Adv Healthc Mater
. 2023 Sep;
12(32):e2301480.
PMID: 37709294
Breast cancer is characterized by an acidic micro-environment. Acidic extracellular pH gives cancer cells an evolutionary advantage, hence, neutralization of the extracellular pH has been considered as a potential therapeutic...
7.
Jardim-Perassi B, Irrera P, Abrahams D, Estrella V, Ordway B, Byrne S, et al.
bioRxiv
. 2023 Sep;
PMID: 37693389
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed...
8.
Jardim-Perassi B, Irrera P, Lau J, Budzevich M, Whelan C, Abrahams D, et al.
Contrast Media Mol Imaging
. 2023 Jan;
2023():1944970.
PMID: 36704211
The extracellular pH (pHe) of solid tumors is often acidic, as a consequence of the Warburg effect, and an altered metabolic state is often associated with malignancy. It has been...
9.
Irrera P, Roberto M, Consolino L, Anemone A, Villano D, Navarro-Tableros V, et al.
Metabolites
. 2023 Jan;
13(1).
PMID: 36676972
Novel anticancer treatments target the pH regulating system that plays a major role in tumor progression by creating an acidic microenvironment, although few studies have addressed their effect on tumor...
10.
Longo D, Pirotta E, Gambino R, Romdhane F, Carella A, Corrado A
Methods Mol Biol
. 2022 Dec;
2614:287-311.
PMID: 36587132
Magnetic resonance imaging (MRI) is a noninvasive imaging technique that allows for physiological and functional studies of the tumor microenvironment. Within MRI, the emerging field of chemical exchange saturation transfer...