Dario I Carrasco
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Explore the profile of Dario I Carrasco including associated specialties, affiliations and a list of published articles.
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17
Citations
191
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Recent Articles
1.
Bryson M, Kloefkorn H, Idlett-Ali S, Carrasco D, Noble D, Martin K, et al.
Pain
. 2024 Aug;
166(2):e27-e35.
PMID: 39106457
Spinal cord injury leads to hyperexcitability and dysfunction in spinal sensory processing. As hyperexcitable circuits can become epileptiform, we explored whether such activity emerges in a thoracic spinal cord injury...
2.
Khan S, Carrasco D, Isaacson R, English A
Front Neuroanat
. 2023 Nov;
17:1303888.
PMID: 38020215
Introduction: Recovery from peripheral nerve injuries is poor because axon regeneration is slow and inefficient. Experimental therapies that increase signaling of neuronal brain-derived neurotrophic factor (BDNF) through its TrkB receptor...
3.
Jing B, Carrasco D, AuYong N, Lindsey B
IEEE Trans Ultrason Ferroelectr Freq Control
. 2023 Sep;
70(12):1749-1760.
PMID: 37721880
A novel transverse velocity spectral estimation method is proposed to estimate the velocity component in the direction transverse to the beam axis for ultrafast imaging. The transverse oscillation was introduced...
4.
Isaacson R, Carrasco D, Holliday H, Kang S, Khan S, Kim D, et al.
Eur J Neurosci
. 2023 Aug;
58(6):3555-3568.
PMID: 37608574
Limited axon regeneration following peripheral nerve injury may be related to activation of the lysosomal protease, asparaginyl endopeptidase (AEP, δ-secretase) and its degradation of the microtubule associated protein, Tau. Activity...
5.
Rotterman T, Carrasco D, Housley S, Nardelli P, Powers R, Cope T
PLoS One
. 2021 Nov;
16(11):e0259918.
PMID: 34797870
The axon initial segment (AIS) responsible for action potential initiation is a dynamic structure that varies and changes together with neuronal excitability. Like other neuron types, alpha motoneurons in the...
6.
Housley S, Rotterman T, Nardelli P, Carrasco D, Noel R, OFarrell L, et al.
Neurotoxicology
. 2021 Aug;
86:162-165.
PMID: 34363843
The persisting need for effective clinical treatment of chemotherapy-induced neurotoxicity (CIN) motivates critical evaluation of preclinical models of CIN for their translational relevance. The present study aimed to provide the...
7.
Housley S, Nardelli P, Carrasco D, Rotterman T, Pfahl E, Matyunina L, et al.
Cancer Res
. 2020 Apr;
80(13):2940-2955.
PMID: 32345673
For the constellation of neurologic disorders known as chemotherapy-induced peripheral neuropathy, mechanistic understanding and treatment remain deficient. Here, we present the first evidence that chronic sensory neuropathy depends on nonlinear...
8.
Carrasco D, Vincent J, Cope T
J Neurophysiol
. 2017 Jan;
117(4):1690-1701.
PMID: 28123009
Knowledge of the molecular mechanisms underlying signaling of mechanical stimuli by muscle spindles remains incomplete. In particular, the ionic conductances that sustain tonic firing during static muscle stretch are unknown....
9.
Carrasco D, Bahr B, Seburn K, Pinter M
Exp Neurol
. 2016 Feb;
278:116-26.
PMID: 26853136
In several animal models of motor neuron disease, degeneration begins in the periphery. Clarifying the possible role of Schwann cells remains a priority. We recently showed that terminal Schwann cells...
10.
Carrasco D, Seburn K, Pinter M
Exp Neurol
. 2015 Sep;
275 Pt 1:172-81.
PMID: 26416261
In mice that express SOD1 mutations found in human motor neuron disease, degeneration begins in the periphery for reasons that remain unknown. At the neuromuscular junction (NMJ), terminal Schwann cells...