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Daria Esterhazy

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Articles 23
Citations 897
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Recent Articles
1.
Campos Canesso M, Canesso M, Castro T, de Castro T, Nakandakari-Higa S, Lockhart A, et al.
Science . 2024 Dec; 387(6739):eado5088. PMID: 39700315
The intestinal immune system must concomitantly tolerate food and commensals and protect against pathogens. Antigen-presenting cells (APCs) orchestrate these immune responses by presenting luminal antigens to CD4 T cells and...
2.
Zhou Y, Komnick M, Sepulveda F, Liu G, Nieves-Ortiz E, Meador K, et al.
bioRxiv . 2024 Nov; PMID: 39484594
The / gene locus encodes for a conserved family of potent antimicrobial but also pancreatitis-associated proteins. Here we investigated whether family members differ in their baseline expression levels and abilities...
3.
Komnick M, Esterhazy D
Trends Immunol . 2023 Aug; 44(10):745-747. PMID: 37591713
Celiac disease (CeD) is an immune disorder characterized by gluten intolerance that can be unleashed by enteric viral infections in mice. However, Sanchez-Medina et al. recently identified a murine commensal...
4.
Brown H, Komnick M, Brigleb P, Dermody T, Esterhazy D
Immunity . 2023 Aug; 56(9):2070-2085.e11. PMID: 37557168
Lymph nodes (LNs) are critical sites for shaping tissue-specific adaptive immunity. However, the impact of LN sharing between multiple organs on such tailoring is less understood. Here, we describe the...
5.
Honer M, Polara A, Kuwabara H, Jacobsen H, Pahler A, Hartung T, et al.
J Labelled Comp Radiopharm . 2023 Apr; 66(9):222-236. PMID: 37095603
The beta-site amyloid precursor protein cleaving enzyme (BACE1) is responsible for initiating the generation of beta-amyloid, the major constituent of amyloid plaques in Alzheimer's disease (AD). The purpose of this...
6.
Wang P, Chen L, McIntosh C, Lane J, Li R, Xie S, et al.
Am J Transplant . 2022 May; 22(10):2348-2359. PMID: 35633180
Oral antigen exposure is a powerful, non-invasive route to induce immune tolerance to dietary antigens, and has been modestly successful at prolonging graft survival in rodent models of transplantation. To...
7.
Brown H, Esterhazy D
Mucosal Immunol . 2021 Jul; 14(6):1259-1270. PMID: 34211125
The emerging concept of tissue specific immunity has opened the gates to new inquiries into what factors drive immune cell niche adaptation and the implications on immune homeostasis, organ specific...
8.
Brown H, Esterhazy D
Immunity . 2020 Dec; 53(6):1128-1130. PMID: 33326762
Although many immune cells can secrete TGF-β, whether all sources of TGF-β are functionally equivalent is unknown. In this issue, Turner et al. uncover the importance of T regulatory (Treg)...
9.
Esterhazy D, Canesso M, Mesin L, Muller P, de Castro T, Lockhart A, et al.
Nature . 2019 Apr; 569(7754):126-130. PMID: 30988509
The intestinal immune system has the challenging task of tolerating foreign nutrients and the commensal microbiome, while excluding or eliminating ingested pathogens. Failure of this balance leads to conditions such...
10.
Esterhazy D, Mucida D
Nature . 2019 Feb; 566(7742):49-50. PMID: 30710125
No abstract available.