Danny W Wilson
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Explore the profile of Danny W Wilson including associated specialties, affiliations and a list of published articles.
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67
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2251
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Recent Articles
1.
Ashton T, Calic P, Dans M, Kang Ooi Z, Zhou Q, Loi K, et al.
ChemMedChem
. 2024 Aug;
19(24):e202400549.
PMID: 39210733
The emergence of resistance against current antimalarial treatments has necessitated the need for the development of novel antimalarial chemotypes. Toward this goal, we recently optimised the antimalarial activity of the...
2.
Angage D, Chmielewski J, Maddumage J, Hesping E, Caiazzo S, Lai K, et al.
Nat Commun
. 2024 Aug;
15(1):7206.
PMID: 39174515
Apical membrane antigen-1 (AMA1) is a conserved malarial vaccine candidate essential for the formation of tight junctions with the rhoptry neck protein (RON) complex, enabling Plasmodium parasites to invade human...
3.
Ashton T, Calic P, Dans M, Kang Ooi Z, Zhou Q, Palandri J, et al.
J Med Chem
. 2024 Aug;
67(16):14493-14523.
PMID: 39134060
To contribute to the global effort to develop new antimalarial therapies, we previously disclosed initial findings on the optimization of the dihydroquinazolinone-3-carboxamide class that targets PfATP4. Here we report on...
4.
Pietsch E, Niedermuller K, Andrews M, Meyer B, Lenz T, Wilson D, et al.
Mol Microbiol
. 2023 Dec;
121(3):529-542.
PMID: 38131156
An essential process in transmission of the malaria parasite to the Anopheles vector is the conversion of mature gametocytes into gametes within the mosquito gut, where they egress from the...
5.
Liffner B, Cepeda Diaz A, Blauwkamp J, Anaguano D, Frolich S, Muralidharan V, et al.
Elife
. 2023 Dec;
12.
PMID: 38108809
Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell biology, but study of these organisms using light microscopy is often hindered by their small size. Ultrastructural expansion microscopy...
6.
Ascari A, Frolich S, Zang M, Tran E, Wilson D, Morona R, et al.
J Bacteriol
. 2023 Nov;
205(12):e0032023.
PMID: 37991380
Bacterial pathogens have vastly distinct sites that they inhabit during infection. This requires adaptation due to changes in nutrient availability and antimicrobial stress. The bacterial surface is a primary barrier,...
7.
Andrews M, Baum J, Gilson P, Wilson D
Trends Parasitol
. 2023 Oct;
39(12):1004-1013.
PMID: 37827961
A critical part of the malaria parasite's life cycle is invasion of red blood cells (RBCs) by merozoites. Inside RBCs, the parasite forms a schizont, which undergoes segmentation to produce...
8.
Dans M, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, et al.
PLoS Biol
. 2023 Apr;
21(4):e3002066.
PMID: 37053271
With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are identified to target Plasmodium falciparum. We have recently described a compound, MMV020291, as a specific inhibitor...
9.
Liffner B, Cepeda Diaz A, Blauwkamp J, Anaguano D, Frolich S, Muralidharan V, et al.
bioRxiv
. 2023 Mar;
PMID: 36993606
Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell biology, but study of these organisms using light microscopy is often hindered by their small size. Ultrastructural expansion microscopy...
10.
Drew D, Wilson D, Weiss G, Yeoh L, Henshall I, Crabb B, et al.
Cell Mol Life Sci
. 2023 Feb;
80(3):74.
PMID: 36847896
Plasmodium falciparum and P. vivax are the major causes of human malaria, and P. knowlesi is an important additional cause in SE Asia. Binding of apical membrane antigen 1 (AMA1)...