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Danny Filer

Explore the profile of Danny Filer including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Urena E, Xu B, Regan J, Atilano M, Minkley L, Filer D, et al.
Proc Natl Acad Sci U S A . 2024 Jan; 121(4):e2311313121. PMID: 38241436
Pharmacological therapies are promising interventions to slow down aging and reduce multimorbidity in the elderly. Studies in animal models are the first step toward translation of candidate molecules into human...
2.
Martinez Corrales G, Filer D, Wenz K, Rogan A, Phillips G, Li M, et al.
Cell Rep . 2020 Feb; 30(6):1661-1669.e4. PMID: 32049000
Health and survival in old age can be improved by changes in gene expression. RNA polymerase (Pol) I is the essential, conserved enzyme whose task is to generate the pre-ribosomal...
3.
Filer D, Thompson M, Takhaveev V, Dobson A, Kotronaki I, Green J, et al.
Nature . 2017 Nov; 552(7684):263-267. PMID: 29186112
Three distinct RNA polymerases transcribe different classes of genes in the eukaryotic nucleus. RNA polymerase (Pol) III is the essential, evolutionarily conserved enzyme that generates short, non-coding RNAs, including tRNAs...