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Danny Allen

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Articles 24
Citations 450
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Recent Articles
1.
Kaeppler J, Chen J, Buono M, Vermeer J, Kannan P, Cheng W, et al.
EMBO Rep . 2022 Jul; 23(9):e53221. PMID: 35848459
The effect of radiation therapy on tumor vasculature has long been a subject of debate. Increased oxygenation and perfusion have been documented during radiation therapy. Conversely, apoptosis of endothelial cells...
2.
Gilchrist S, Kinchesh P, Kersemans V, Beech J, Allen D, Brady M, et al.
Magn Reson Imaging . 2021 Apr; 81:1-9. PMID: 33905831
Prospective cardiac gating during MRI is hampered by electromagnetic induction from the rapidly switched imaging gradients into the ECG detection circuit. This is particularly challenging in small animal MRI, as...
3.
Lauder S, Smart K, Kersemans V, Allen D, Scott J, Pires A, et al.
J Immunother Cancer . 2020 Oct; 8(2). PMID: 33093155
Background: Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme...
4.
Mosley M, Torres J, Allen D, Cornelissen B
Nucl Med Biol . 2020 Mar; 84-85:73-79. PMID: 32135474
Purpose: Molecular imaging of cancer cells' reaction to radiation damage can provide a non-invasive measure of tumour response to treatment. The cell surface glycoprotein ICAM-1 (CD54) was identified as a...
5.
Thomas E, Menon J, Owen J, Skaripa-Koukelli I, Wallington S, Gray M, et al.
Theranostics . 2019 Sep; 9(19):5595-5609. PMID: 31534505
Nanomedicines allow active targeting of cancer for diagnostic and therapeutic applications through incorporation of multiple functional components. Frequently, however, clinical translation is hindered by poor intratumoural delivery and distribution. The...
6.
Roque T, Risser L, Kersemans V, Smart S, Allen D, Kinchesh P, et al.
IEEE Trans Med Imaging . 2018 Mar; 37(3):724-732. PMID: 29533893
Predicting tumor growth and its response to therapy remains a major challenge in cancer research and strongly relies on tumor growth models. In this paper, we introduce, calibrate, and verify...
7.
Andreou K, Soto M, Allen D, Economopoulos V, de Bernardi A, Larkin J, et al.
Front Oncol . 2017 Nov; 7:251. PMID: 29164051
Brain metastasis is a common complication of cancer patients and is associated with poor survival. Histological data from patients with brain metastases suggest that microglia are the major immune population...
8.
Torres J, Knight J, Mosley M, Kersemans V, Koustoulidou S, Allen D, et al.
Mol Imaging Biol . 2017 Aug; 20(2):292-299. PMID: 28842811
Purpose: Despite its widespread use, the positron emission tomography (PET) radiotracer 2-deoxy-2-[F]fluoro-D-glucose ([F]FDG) has been shown in clinical settings to be ineffective for improving early diagnosis of pancreatic ductal adenocarcinoma...
9.
Patel N, Able S, Allen D, Fokas E, Cornelissen B, Gleeson F, et al.
EJNMMI Res . 2017 Jun; 7(1):49. PMID: 28560583
Background: The ability to image vascular endothelial growth factor (VEGF) could enable prospective, non-invasive monitoring of patients receiving anti-angiogenic therapy. This study investigates the specificity and pharmacokinetics of In-bevacizumab binding...
10.
Roque T, Kersemans V, Smart S, Allen D, Schnabel J, Chappell M
Annu Int Conf IEEE Eng Med Biol Soc . 2017 Mar; 2016:5949-5952. PMID: 28269607
Imaging-based modelling of tumour growth can serve as a powerful tool to understand and predict tumour evolution and its response to therapy. The purpose of this study was to introduce,...