Danielle van Westen
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Explore the profile of Danielle van Westen including associated specialties, affiliations and a list of published articles.
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153
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3945
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Recent Articles
1.
Georgiopoulos C, Werlin A, Lasic S, Hall S, van Westen D, Spotorno N, et al.
Brain Commun
. 2024 Dec;
6(6):fcae421.
PMID: 39713238
Non-invasive evaluation of glymphatic function has emerged as a crucial goal in neuroimaging, and diffusion tensor imaging along the perivascular space (DTI-ALPS) has emerged as a candidate method for this...
2.
Wuestefeld A, Binette A, van Westen D, Strandberg O, Stomrud E, Mattsson-Carlgren N, et al.
Alzheimers Res Ther
. 2024 Sep;
16(1):204.
PMID: 39285454
Background: The medial temporal lobe (MTL) is hypothesized to be relatively spared in early-onset Alzheimer's disease (EOAD). Yet, detailed examination of MTL subfields and drivers of atrophy in amnestic EOAD...
3.
Wisse L, Spotorno N, Rossi M, Grothe M, Mammana A, Tideman P, et al.
JAMA Neurol
. 2024 Jul;
81(10):1051-1059.
PMID: 39068668
Importance: The lack of an in vivo measure for α-synuclein (α-syn) pathology until recently has limited thorough characterization of its brain atrophy pattern, especially during early disease stages. Objective: To...
4.
Lerch O, Ferreira D, Stomrud E, van Westen D, Tideman P, Palmqvist S, et al.
Alzheimers Res Ther
. 2024 Jul;
16(1):153.
PMID: 38970077
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of clinical symptoms. Analysis of brain atrophy patterns using structural MRI and multivariate...
5.
Hristovska I, Binette A, Kumar A, Gaiteri C, Karlsson L, Strandberg O, et al.
medRxiv
. 2024 Jul;
PMID: 38947084
The pathophysiology underlying various manifestations of cerebral small vessel disease (cSVD) remains obscure. Using cerebrospinal fluid proximity extension assays and co-expression network analysis of 2,943 proteins, we found common and...
6.
Santillo A, Strandberg T, Reislev N, Nilsson M, Stomrud E, Spotorno N, et al.
Neuroimage
. 2024 Jun;
296:120672.
PMID: 38851551
Age-related white matter hyperintensities are a common feature and are known to be negatively associated with structural integrity, functional connectivity, and cognitive performance. However, this has yet to be fully...
7.
Wuestefeld A, Binette A, van Westen D, Strandberg O, Stomrud E, Mattsson-Carlgren N, et al.
bioRxiv
. 2024 Jun;
PMID: 38826333
Background: The medial temporal lobe (MTL) is hypothesized to be relatively spared in early-onset Alzheimer's disease (EOAD). Yet, detailed examination of MTL subfield volumes and drivers of atrophy in amnestic...
8.
A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings
Baumeister H, Vogel J, Insel P, Kleineidam L, Wolfsgruber S, Stark M, et al.
Brain
. 2024 Apr;
147(7):2400-2413.
PMID: 38654513
Memory clinic patients are a heterogeneous population representing various aetiologies of pathological ageing. It is not known whether divergent spatiotemporal progression patterns of brain atrophy, as previously described in Alzheimer's...
9.
Fixel-Based Analysis Reveals Tau-Related White Matter Changes in Early Stages of Alzheimer's Disease
Ahmadi K, Pereira J, van Westen D, Pasternak O, Zhang F, Nilsson M, et al.
J Neurosci
. 2024 Apr;
44(18).
PMID: 38565289
Several studies have shown white matter (WM) abnormalities in Alzheimer's disease (AD) using diffusion tensor imaging (DTI). Nonetheless, robust characterization of WM changes has been challenging due to the methodological...
10.
Spotorno N, Najac C, Strandberg O, Stomrud E, van Westen D, Nilsson M, et al.
Brain Commun
. 2024 Feb;
6(1):fcae026.
PMID: 38370447
In Alzheimer's disease, reconfiguration and deterioration of tissue microstructure occur before substantial degeneration become evident. We explored the diffusion properties of both water, a ubiquitous marker measured by diffusion MRI,...