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» Authors » Danielle Silveira Macedo

Danielle Silveira Macedo

Explore the profile of Danielle Silveira Macedo including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 42
Citations 521
Followers 0
Related Specialties
Pharmacology
Neurology
Psychology
Top 10 Co-Authors
Francisca Clea Florenco de Sousa
Silvania Maria Mendes Vasconcelos
Glauce Socorro de Barros Viana
Maria Izabel Gomes Silva
Brinell Arcanjo Moura
Fernanda Yvelize Ramos de Araujo
Silvania Maria Mendes de Vasconcelos
Glauce Socorro Barros Viana
Gersilene Valente de Oliveira
Jose Maria Barbosa Filho
Published In
Fundam Clin Pharmacol
Epilepsy Behav
Behav Brain Res
J Pharm Pharmacol
Neurosci Lett
Affiliations
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Recent Articles
1.
Cyclooxygenase-2 inhibitors alleviated depressive and anxious-like behaviors in mice exposed to lipopolysaccharide: Involvement of oxidative stress and neuroinflammation
da Silva D, Sales I, Oliveira J, Dos Santos Junior M, Reboucas M, Valentim J, et al.
Pharmacol Biochem Behav . 2024 Apr; 240():173778. PMID: 38679081
Depression and anxiety disorders have their pathophysiologies linked to inflammation and oxidative stress. In this context, celecoxib (CLX) and etoricoxib (ETR) inhibit cyclooxygenase 2 (COX-2), an enzyme expressed by cells...
2.
Cognitive dysfunction in systemic lupus erythematosus is associated with disease activity and oxidative stress: a comparative study with rheumatoid arthritis for identifying biomarkers
de Sousa D, Tavares Sobreira E, Feitosa W, Aires T, Araujo L, Silva A, et al.
BMC Neurosci . 2023 Dec; 24(1):66. PMID: 38093175
Background: The prevalence and pathophysiological mechanisms of cognitive deficits (CD) Systemic Lupus Erythematosus (SLE) and Rheumatoid arthritis (RA) are very heterogeneous and poorly understood. We characterized CD in patients with...
3.
Involvement of oxidative pathways and BDNF in the antidepressant effect of carvedilol in a depression model induced by chronic unpredictable stress
de Sousa C, da Silva Medeiros I, Vasconcelos G, de Aquino G, Filho F, de Almeida Cysne J, et al.
Psychopharmacology (Berl) . 2022 Jan; 239(1):297-311. PMID: 35022822
Rationale: Depression is a severe psychiatric disorder with oxidative imbalance and neurotrophic deficits as underlying mechanisms. Objectives: Based on the antioxidant effects of carvedilol (CARV), here, we aimed to evaluate...
4.
Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression
Oliveira T, Chaves Filho A, Juca P, Soares M, Cunha N, Vieira C, et al.
Behav Brain Res . 2021 Nov; 419:113667. PMID: 34798169
Mirtazapine (MIRT) is a multi-target antidepressant used in treatment of severe depression with promising efficacy, but also with important side effects, mainly sedation and weight gain. Thus, the present study...
5.
Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 mediates acute kidney injury by oxidative stress and release of inflammatory cytokines
Marinho A, Silveira J, Chaves Filho A, Coelho Jorge A, Nogueira Junior F, Pereira V, et al.
Toxicon . 2020 Dec; 190:31-38. PMID: 33307108
The envenomation caused by the Bothrops pauloensis snake leads to severe local and systemic effects including acute kidney injury. In this study, we investigated the renal effects by phospholipases A2...
6.
Involvement of monoaminergic targets in the antidepressant- and anxiolytic-like effects of the synthetic alkamide riparin IV: Elucidation of further mechanisms through pharmacological, neurochemistry and computational approaches
Sartori D, Oliveira N, Valentim J, Silva D, Mallman A, Oliveira I, et al.
Behav Brain Res . 2020 Jan; 383:112487. PMID: 31987932
Despite recent advances, current antidepressants have considerable limitations: late onset of action and the high profile of refractoriness. Biomedical research with natural products has gained growing interest in the last...
7.
Thymol reverses depression-like behaviour and upregulates hippocampal BDNF levels in chronic corticosterone-induced depression model in female mice
Capibaribe V, Vasconcelos Mallmann A, Lopes I, Maia Oliveira I, Ferreira de Oliveira N, Chaves R, et al.
J Pharm Pharmacol . 2019 Oct; 71(12):1774-1783. PMID: 31608449
Objectives: Based on this, the central therapeutic effects of thymol were verified in the neurotrophic pathway. Methods: Female swiss mice were divided into four groups: control, corticosterone (Cort), thymol (Cort...
8.
Evidence for Host Epigenetic Signatures Arising From Arbovirus Infections: A Systematic Review
de Aguiar G, Leite C, Dias B, Vasconcelos S, de Moraes R, de Moraes M, et al.
Front Immunol . 2019 Jun; 10:1207. PMID: 31214179
Arbovirus infections have steadily become a major pandemic threat. This study aimed at investigating the existence of host epigenetic markers arising from the principal arboviruses infections impacting on human health....
9.
Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice
Chaves R, Vasconcelos Mallmann A, Oliveira N, Maia Oliveira I, Capibaribe V, da Silva D, et al.
Pharmacol Biochem Behav . 2019 Mar; 180:44-51. PMID: 30904544
Mental disorders have a multifactorial etiology and stress presents as one of the causal factors. In depression, it is suggested that high cortisol concentration contributes directly to the pathology of...
10.
Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms
Lopes I, Maia Oliveira I, Capibaribe V, Valentim J, da Silva D, de Souza A, et al.
Neurochem Int . 2018 Jul; 120:33-42. PMID: 30041016
Riparin II (RIP II) is an alkamide isolated from Aniba riparia that has presented antidepressant and anxiolytic effects in acute stress behavioral models. This study aimed to investigate the activity...