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Danielle L Schmitt

Explore the profile of Danielle L Schmitt including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 229
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Recent Articles
1.
Ranzau B, Robinson T, Scully J, Kapelczak E, Dean T, TeSlaa T, et al.
ACS Bio Med Chem Au . 2025 Feb; 5(1):184-193. PMID: 39990938
Malonyl-CoA is the essential building block of fatty acids and regulates cell function through protein malonylation and allosteric regulation of signaling networks. Accordingly, the production and use of malonyl-CoA is...
2.
Ranzau B, Robinson T, Scully J, Kapelczack E, Dean T, TeSlaa T, et al.
bioRxiv . 2024 Oct; PMID: 39386450
Malonyl-CoA is the essential building block of fatty acids and regulates cell function through protein malonylation and allosteric regulation of signaling networks. Accordingly, the production and use of malonyl-CoA is...
3.
Jeon M, Schmitt D, Kyoung M, An S
ACS Bio Med Chem Au . 2023 Oct; 3(5):461-470. PMID: 37876499
Enzymes in glucose metabolism have been subjected to numerous studies, revealing the importance of their biological roles during the cell cycle. However, due to the lack of viable experimental strategies...
4.
Schmitt D, Dranchak P, Parajuli P, Blivis D, Voss T, Kohnhorst C, et al.
PLoS One . 2023 Aug; 18(8):e0289707. PMID: 37540718
We have previously demonstrated that human liver-type phosphofructokinase 1 (PFK1) recruits other rate-determining enzymes in glucose metabolism to organize multienzyme metabolic assemblies, termed glucosomes, in human cells. However, it has...
5.
Schmitt D
Curr Protoc . 2023 May; 3(5):e771. PMID: 37166284
Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a master regulator of cellular metabolism, phosphorylating a variety of downstream targets throughout the cell. Subcellular AMPK activity results in regulation of glycolysis,...
6.
Liu L, Wang Y, Schmitt D
ACS Cent Sci . 2023 May; 9(4):593-596. PMID: 37122472
No abstract available.
7.
Peng Q, Huang Z, Sun K, Liu Y, Yoon C, Harrison R, et al.
Nat Commun . 2022 Dec; 13(1):7933. PMID: 36566209
Genome architecture and organization play critical roles in cell life. However, it remains largely unknown how genomic loci are dynamically coordinated to regulate gene expression and determine cell fate at...
8.
Schmitt D, Mehta S, Zhang J
Curr Opin Chem Biol . 2022 Nov; 71:102224. PMID: 36347198
Precise spatiotemporal organization and regulation of signal transduction networks are essential for cellular response to internal and external cues. To understand how this biochemical activity architecture impacts cellular function, many...
9.
Schmitt D, Curtis S, Lyons A, Zhang J, Chen M, He C, et al.
Nat Commun . 2022 Jul; 13(1):3856. PMID: 35790710
AMP-activated protein kinase (AMPK) is a master regulator of cellular energetics which coordinates metabolism by phosphorylating a plethora of substrates throughout the cell. But how AMPK activity is regulated at...
10.
Schmitt D, Mehta S, Zhang J
Curr Opin Chem Biol . 2020 Jan; 54:63-69. PMID: 31911398
Genetically encoded fluorescent protein-based kinase biosensors are a central tool for illumination of the kinome. The adaptability and versatility of biosensors have allowed for spatiotemporal observation of real-time kinase activity...