Danielle K Manning
Overview
Explore the profile of Danielle K Manning including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
503
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rana H, Koeller D, Walker M, Unal B, Levine A, Chittenden A, et al.
Cancers (Basel)
. 2024 Mar;
16(5).
PMID: 38473309
Standard methods of variant assessment in hereditary cancer susceptibility genes are limited by the lack of availability of key supporting evidence. In cancer, information derived from tumors can serve as...
2.
Isidro R, Chittenden A, Walker M, Schwartz A, Koeller D, Hayes C, et al.
Front Oncol
. 2024 Feb;
13:1284690.
PMID: 38344144
The presence of variants of uncertain significance (VUS) in DNA mismatch repair (MMR) genes leads to uncertainty in the clinical management of patients being evaluated for Lynch syndrome (LS). Currently,...
3.
Neil A, Chukwueke U, Hoover N, Marris S, Rojas-Rudilla V, Manning D, et al.
Cancer Cytopathol
. 2023 Oct;
132(4):214-223.
PMID: 37812603
Background: Leptomeningeal metastases occur across multiple solid and lymphoid cancers, and patients typically undergo cytopathologic assessment of cerebrospinal fluid (CSF) in this setting. For patients diagnosed with metastatic cancer, the...
4.
Schwartz A, Manning D, Koeller D, Chittenden A, Isidro R, Hayes C, et al.
Front Oncol
. 2022 Sep;
12:942741.
PMID: 36091175
Genomic profiles of tumors are often unique and represent characteristic mutational signatures defined by DNA damage or DNA repair response processes. The tumor-derived somatic information has been widely used in...
5.
Siegmund S, Manning D, Davineni P, Dong F
Mod Pathol
. 2022 Jul;
35(10):1458-1467.
PMID: 35902772
Tumor purity, or the relative contribution of tumor cells out of all cells in a pathological specimen, influences mutation identification and clinical interpretation of cancer panel next generation sequencing results....
6.
Koeller D, Manning D, Schwartz A, Chittenden A, Hayes C, Abraamyan F, et al.
MethodsX
. 2022 Jul;
9:101761.
PMID: 35774415
The interpretation of hereditary genetic sequencing variants is often limited due to the absence of functional data and other key evidence to assess the role of variants in disease. Cancer...
7.
Schienda J, Church A, Corson L, Decker B, Clinton C, Manning D, et al.
JCO Precis Oncol
. 2021 Dec;
5.
PMID: 34964003
Purpose: Molecular tumor profiling is becoming a routine part of clinical cancer care, typically involving tumor-only panel testing without matched germline. We hypothesized that integrated germline sequencing could improve clinical...
8.
Manning D, Shivdasani P, Koeller D, Schwartz A, Rana H, Garber J, et al.
Data Brief
. 2021 Dec;
39:107653.
PMID: 34934780
Von Hippel-Lindau (VHL) syndrome is a hereditary cancer genetic condition associated with inactivating pathogenic alterations in the tumor suppressor gene located at 3p (short arm of chromosome 3). Classic features...
9.
Rana H, Koeller D, Schwartz A, Manning D, Schneider K, Krajewski K, et al.
Eur J Med Genet
. 2021 Oct;
64(12):104359.
PMID: 34628056
Von Hippel-Lindau (VHL) syndrome is a hereditary tumor syndrome associated with germline loss-of-function pathogenic variants (PVs) in the VHL gene. VHL is classically associated with a high penetrance for many...
10.
Li Y, Schmidt R, Manning D, Jia Y, Dong F
Arch Pathol Lab Med
. 2021 May;
146(2):227-232.
PMID: 34015814
Context.—: The presence of allogeneic contamination impacts clinical reporting in cancer next-generation sequencing specimens. Although consensus guidelines recommend the identification of contaminating DNA as a part of quality control, implementation...