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Danielle Burger

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Articles 31
Citations 887
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Recent Articles
1.
Burger D, Fickentscher C, Moerloose P, Brandt K
Sci Rep . 2016 Jul; 6:29834. PMID: 27431477
NLRP3 and ASC are able to form a large multimeric complex called inflammasome in response to a number danger signals. The NLRP3 inflammasome is required for the activation of caspase-1...
2.
Scanu A, Luisetto R, Oliviero F, Gruaz L, Sfriso P, Burger D, et al.
Ann Rheum Dis . 2013 Dec; 74(3):587-94. PMID: 24326007
Objectives: To investigate the effects and mechanisms of action of high-density lipoproteins (HDL) in monosodium urate (MSU) crystal-induced inflammation -that is, gouty inflammation, in vivo. Methods: Air pouches raised on...
3.
Jornot L, Cordey S, Caruso A, Gerber C, Vukicevic M, Tapparel C, et al.
PLoS One . 2011 Oct; 6(10):e26293. PMID: 22022590
Hypothesis: T cells modulate the antiviral and inflammatory responses of airway epithelial cells to human rhinoviruses (HRV). Methods: Differentiated primary human nasal epithelial cells (HNEC) grown on collagen-coated filters were...
4.
Carpintero R, Burger D
Commun Integr Biol . 2011 Apr; 4(1):112-4. PMID: 21509198
Imbalance in cytokine homeostasis plays an important part in the pathogenesis of various chronic inflammatory diseases. In multiple sclerosis (MS), the pro-inflammatory cytokine interleukin-1β (IL-1β) is present in the central...
5.
Lalive P, Neuhaus O, Benkhoucha M, Burger D, Hohlfeld R, Zamvil S, et al.
CNS Drugs . 2011 Apr; 25(5):401-14. PMID: 21476611
Glatiramer acetate is a synthetic, random copolymer widely used as a first-line agent for the treatment of relapsing-remitting multiple sclerosis (MS). While earlier studies primarily attributed its clinical effect to...
6.
Satta N, Kruithof E, Fickentscher C, Dunoyer-Geindre S, Boehlen F, Reber G, et al.
Blood . 2011 Feb; 117(20):5523-31. PMID: 21330474
The presence of antiphospholipid antibodies (aPLAs) is associated with arterial or venous thrombosis and/or recurrent fetal loss. The proposed pathogenic mechanisms for aPLA effects include the inflammatory activation of monocytes...
7.
Carpintero R, Brandt K, Gruaz L, Molnarfi N, Lalive P, Burger D
Proc Natl Acad Sci U S A . 2010 Sep; 107(41):17692-7. PMID: 20876102
Glatiramer acetate (GA), an immunomodulator used in multiple sclerosis (MS) therapy, induces the production of secreted IL-1 receptor antagonist (sIL-1Ra), a natural inhibitor of IL-1β, in human monocytes, and in...
8.
Brandt K, Carpintero R, Gruaz L, Molnarfi N, Burger D
J Leukoc Biol . 2010 Sep; 88(6):1191-200. PMID: 20837746
IFN-β and sIL-1Ra play crucial roles in the regulation of innate immunity and inflammation. IFN-β, which is widely used to improve the course of relapsing, remitting multiple sclerosis, induces the...
9.
Carpintero R, Gruaz L, Brandt K, Scanu A, Faille D, Combes V, et al.
PLoS One . 2010 Aug; 5(7):e11869. PMID: 20686620
Background: Direct cellular contact with stimulated T cells is a potent mechanism that induces cytokine production in human monocytes in the absence of an infectious agent. This mechanism is likely...
10.
Gruaz L, Delucinge-Vivier C, Descombes P, Dayer J, Burger D
PLoS One . 2010 Mar; 5(2):e9418. PMID: 20195532
Background: Cellular contact with stimulated T cells is a potent inducer of cytokine production in human monocytes and is likely to play a substantial part in chronic/sterile inflammatory diseases. High-density...