Daniela Merlo
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Explore the profile of Daniela Merlo including associated specialties, affiliations and a list of published articles.
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36
Citations
777
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Recent Articles
1.
Mollinari C, Cardinale A, Lupacchini L, Martire A, Chiodi V, Martinelli A, et al.
EMBO Rep
. 2024 Jul;
25(8):3707-3737.
PMID: 39085642
The key DNA repair enzyme DNA-PKcs has several and important cellular functions. Loss of DNA-PKcs activity in mice has revealed essential roles in immune and nervous systems. In humans, DNA-PKcs...
2.
Merlo D, Mollinari C
Curr Alzheimer Res
. 2023 Nov;
20(8):523-525.
PMID: 37921166
No abstract available.
3.
Mollinari C, De Dominicis C, Lupacchini L, Sansone L, Caprini D, Casciola C, et al.
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216271
Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are clinically diagnosed using neuropsychological and cognitive tests, expensive neuroimaging-based approaches (MRI and PET) and invasive and time-consuming lumbar puncture for...
4.
Cardinale A, Saladini S, Lupacchini L, Ruspantini I, De Dominicis C, Papale M, et al.
Mol Biol Rep
. 2021 Nov;
49(2):1089-1101.
PMID: 34797489
Background: Emerging evidence suggest that DNA-PK complex plays a role in the cellular response to oxidative stress, in addition to its function of double strand break (DSB) repair. In this...
5.
Mollinari C, Merlo D
Neurochem Res
. 2021 Mar;
46(6):1330-1336.
PMID: 33666839
Translating successful preclinical research in neurodegenerative diseases into clinical practice has been difficult. The preclinical disease models used for testing new drugs not always appear predictive of the effects of...
6.
Lupacchini L, Maggi F, Tomino C, De Dominicis C, Mollinari C, Fini M, et al.
Molecules
. 2020 Dec;
26(1).
PMID: 33379366
(1) Background: Nicotine is implicated in the SARS-COV-2 infection through activation of the α7-nAChR and over-expression of ACE2. Our objective was to clarify the role of nicotine in SARS-CoV-2 infection...
7.
Lu J, Li Y, Mollinari C, Garaci E, Merlo D, Pei G
Curr Alzheimer Res
. 2019 Oct;
16(10):934-949.
PMID: 31642778
Background: Amyloid-β42 oligomers (Aβ42O), the proximate effectors of neurotoxicity observed in Alzheimer's disease (AD), can induce mitochondrial oxidative stress and impair mitochondrial function besides causing mitochondrial DNA (mtDNA) damage. Aβ42O...
8.
Vernone A, Ricca C, Merlo D, Pescarmona G, Silvagno F
R Soc Open Sci
. 2019 Jun;
6(4):181891.
PMID: 31183125
In this study, we investigated whether the relative abundance of glutamate and glutamine in human proteins reflects the availability of these amino acids (AAs) dictated by the cellular context. In...
9.
Pietrasanta C, Pugni L, Merlo D, Acaia B, Consonni D, Ronchi A, et al.
PLoS One
. 2019 Feb;
14(2):e0211484.
PMID: 30735531
Objective: To investigate the impact of different stages of intrauterine inflammation (IUI) on neonatal outcomes, before and after adjusting for gestational age (GA) and other perinatal confounders. Methods: This was...
10.
Mollinari C, Zhao J, Lupacchini L, Garaci E, Merlo D, Pei G
Cell Death Dis
. 2018 Aug;
9(8):830.
PMID: 30082779
Neurodegenerative diseases are characterized by a gradual loss of cognitive and physical functions. Medications for these disorders are limited and treat the symptoms only. There are no disease-modifying therapies available,...