Daniel W Thomson
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Explore the profile of Daniel W Thomson including associated specialties, affiliations and a list of published articles.
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8
Citations
1945
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Recent Articles
1.
Thomson D, Shahrin N, Wang P, Wadham C, Shanmuganathan N, Scott H, et al.
Leukemia
. 2020 Feb;
34(8):2051-2063.
PMID: 32076119
Blast crisis of chronic myeloid leukemia is associated with poor survival and the accumulation of genomic lesions. Using whole-exome and/or RNA sequencing of patients at chronic phase (CP, n = ...
2.
Thomson D, Dinger M
Nat Rev Genet
. 2016 Apr;
17(5):272-83.
PMID: 27040487
The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with shared microRNA (miRNA) binding sites compete for post-transcriptional control. This hypothesis has gained substantial attention as a unifying function for...
3.
Thomson D, Pillman K, Anderson M, Lawrence D, Toubia J, Goodall G, et al.
Nucleic Acids Res
. 2014 Dec;
43(1):470-81.
PMID: 25452337
High-throughput sequencing reveals an abundance of microRNA-sized fragments derived from larger non-coding RNAs. Roles for these small RNAs in gene silencing are suggested by their co-precipitation with Argonaute, the microRNA...
4.
Quek X, Thomson D, Maag J, Bartonicek N, Signal B, Clark M, et al.
Nucleic Acids Res
. 2014 Oct;
43(Database issue):D168-73.
PMID: 25332394
Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a...
5.
Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion
Bracken C, Li X, Wright J, Lawrence D, Pillman K, Salmanidis M, et al.
EMBO J
. 2014 Jul;
33(18):2040-56.
PMID: 25069772
The microRNAs of the miR-200 family maintain the central characteristics of epithelia and inhibit tumor cell motility and invasiveness. Using the Ago-HITS-CLIP technology for transcriptome-wide identification of direct microRNA targets...
6.
Thomson D, Bracken C, Szubert J, Goodall G
PLoS One
. 2013 Jan;
8(1):e55214.
PMID: 23358900
The ability to alter microRNA (miRNA) abundance is crucial for studying miRNA function. To achieve this there is widespread use of both exogenous double-stranded miRNA mimics for transient over-expression, and...
7.
Thomson D, Bracken C, Goodall G
Nucleic Acids Res
. 2011 Jun;
39(16):6845-53.
PMID: 21652644
MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression in most biological processes. They act by guiding the RNAi-induced silencing complex (RISC) to partially complementary sequences in target mRNAs to...
8.
Bracken C, Szubert J, Mercer T, Dinger M, Thomson D, Mattick J, et al.
Nucleic Acids Res
. 2011 Mar;
39(13):5658-68.
PMID: 21427086
The Ago2 component of the RNA-induced silencing complex (RISC) is an endonuclease that cleaves mRNAs that base pair with high complementarity to RISC-bound microRNAs. Many examples of such direct cleavage...