Daniel W Fults
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Explore the profile of Daniel W Fults including associated specialties, affiliations and a list of published articles.
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38
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1746
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Recent Articles
11.
Huang L, Cohen A, Colman H, Jensen R, Fults D, Couldwell W
Oncotarget
. 2016 Nov;
8(1):191-202.
PMID: 27852048
Mutations of the isocitrate dehydrogenase (IDH) 1 and 2 genes occur in ~80% of lower-grade (WHO grade II and grade III) gliomas. Mutant IDH produces (R)-2-hydroxyglutarate, which induces DNA hypermethylation...
12.
13.
Morrissy A, Garzia L, Shih D, Zuyderduyn S, Huang X, Skowron P, et al.
Nature
. 2016 Jan;
529(7586):351-7.
PMID: 26760213
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon-driven, functional genomic mouse model...
14.
Jenkins N, Rao G, Eberhart C, Pedone C, Dubuc A, Fults D
J Neurooncol
. 2015 Nov;
126(3):415-24.
PMID: 26518543
A highly aggressive subgroup of the pediatric brain tumor medulloblastoma is characterized by overexpression of the proto-oncogene c-Myc, which encodes a transcription factor that normally maintains neural progenitor cells in...
15.
Fults D, Chen T, Bruce J
Neurosurg Focus
. 2015 Mar;
38(3):E1.
PMID: 25727218
No abstract available.
16.
Jenkins N, Kalra R, Dubuc A, Sivakumar W, Pedone C, Wu X, et al.
Acta Neuropathol Commun
. 2014 Jul;
2:85.
PMID: 25059231
Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain...
17.
Mazur M, Nguyen V, Fults D
Case Rep Neurol Med
. 2012 Sep;
2012:816873.
PMID: 22937360
Corticosteroid-induced reduction in contrast enhancement on radiographic imaging is most commonly associated with lymphoma but has been reported in other entities, including glioma. This finding may represent a diagnostic dilemma....
18.
Mumert M, Dubuc A, Wu X, Northcott P, Chin S, Pedone C, et al.
Cancer Res
. 2012 Aug;
72(19):4944-53.
PMID: 22875024
Medulloblastomas are malignant brain tumors that arise in the cerebellum in children and disseminate via the cerebrospinal fluid to the leptomeningeal spaces of the brain and spinal cord. Challenged by...
19.
Wu X, Northcott P, Dubuc A, Dupuy A, Shih D, Witt H, et al.
Nature
. 2012 Feb;
482(7386):529-33.
PMID: 22343890
Medulloblastoma, the most common malignant paediatric brain tumour, arises in the cerebellum and disseminates through the cerebrospinal fluid in the leptomeningeal space to coat the brain and spinal cord. Dissemination,...
20.
Doucette T, Yang Y, Pedone C, Kim J, Dubuc A, Northcott P, et al.
Neurosurgery
. 2011 Nov;
70(4):1003-10.
PMID: 22037313
Background: A significant number of medulloblastomas (MBs) originate from abnormal activation of the sonic hedgehog/patched (SHH/PTC) signaling pathway. Although p53 deficiency enhances tumor formation in mice, inactivation of the p53...