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Daniel Trachsel

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Articles 55
Citations 420
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Recent Articles
1.
Zeng J, Usemann J, Singh K, Jochmann A, Trachsel D, Frey U, et al.
iScience . 2024 Dec; 27(12):111446. PMID: 39697593
Asthma is a widespread respiratory disease affecting millions of children. Salbutamol is a well-established bronchodilator available to treat asthma. However, response to bronchodilators is very heterogeneous, particularly in children. Pharmacometabolomics...
2.
Steinberg R, Mostacci N, Kieninger E, Frauchiger B, Casaulta C, Usemann J, et al.
Commun Med (Lond) . 2024 Nov; 4(1):246. PMID: 39580540
Background: Respiratory tract infections (RTIs) drive lung function decline in children with cystic fibrosis (CF). While the respiratory microbiota is clearly associated with RTI pathogenesis in infants without CF, data...
3.
Wolf L, Usemann J, Collaud E, Derkenne M, Fischer R, Hensen M, et al.
J Cyst Fibros . 2023 Nov; 23(3):506-511. PMID: 37996316
Background: Good data quality is essential when rare disease registries are used as a data source for pharmacovigilance studies. This study investigated data quality of the Swiss cystic fibrosis (CF)...
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Magnolini R, Schneider M, Schori D, Trachsel D, Bruggmann P
Int J Drug Policy . 2023 Feb; 114:103972. PMID: 36841217
Background: Drug checking services (DCS) are harm reduction interventions for people who consume illicit substances. Unregulated drug markets lead to samples with unexpected and variable contents. A retrospective data analysis...
6.
Halberstadt A, Luethi D, Hoener M, Trachsel D, Brandt S, Liechti M
Psychopharmacology (Berl) . 2022 Dec; 240(1):115-126. PMID: 36477925
Rationale: 4-Thio-substituted phenylalkylamines such as 2,5-dimethoxy-4-ethylthiophenethylamine (2C-T-2) and 2,5-dimethoxy-4-n-propylthiophenethylamine (2C-T-7) produce psychedelic effects in humans and have been distributed as recreational drugs. Objectives: The present studies were conducted to examine...
7.
Kolaczynska K, Ducret P, Trachsel D, Hoener M, Liechti M, Luethi D
Eur Neuropsychopharmacol . 2022 Apr; 59:9-22. PMID: 35378384
3,4-methylenedioxyamphetamine (MDA) is a psychoactive compound chemically related to the entactogen MDMA. MDA shares some of the entactogenic effects of MDMA but also exerts stimulant effects and psychedelic properties at...
8.
Kolaczynska K, Luethi D, Trachsel D, Hoener M, Liechti M
Front Pharmacol . 2022 Feb; 12:794254. PMID: 35222010
3,4,5-Trimethoxyphenethylamine (mescaline) is a psychedelic alkaloid found in peyote cactus. Related 4-alkoxy-3,5-dimethoxy-substituted phenethylamines (scalines) and amphetamines (3C-scalines) are reported to induce similarly potent psychedelic effects and are therefore potential novel...
9.
Trachsel D, Erb T, Hammer J, von Ungern-Sternberg B
Paediatr Anaesth . 2021 Dec; 32(2):108-117. PMID: 34877744
Various developmental aspects of respiratory physiology put infants and young children at an increased risk of respiratory failure, which is associated with a higher rate of critical incidents during anesthesia....
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Burgin C, Simmen P, Gupta N, Suter L, Kreuzer S, Haeberlin A, et al.
Pediatr Res . 2021 Oct; 91(3):572-580. PMID: 34601494
Background: Apnea of prematurity cannot be reliably measured with current monitoring techniques. Instead, indirect parameters such as oxygen desaturation or bradycardia are captured. We propose a Kalman filter-based detection of...