Daniel T Laskowitz
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Explore the profile of Daniel T Laskowitz including associated specialties, affiliations and a list of published articles.
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176
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4079
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Recent Articles
1.
Wang H, Dingledine R, Myers S, Traynelis S, Fang C, Tan Y, et al.
J Pharmacol Exp Ther
. 2025 Feb;
392(1):100046.
PMID: 39892986
Aneurysmal subarachnoid hemorrhage (SAH) may be associated with cerebral vasospasm, which can lead to delayed cerebral ischemia, infarction, and worsened functional outcomes. The delayed nature of cerebral ischemia secondary to...
2.
Wongsripuemtet P, Ohnuma T, Minic Z, Vavilala M, Miller J, Laskowitz D, et al.
J Clin Med
. 2025 Jan;
14(2).
PMID: 39860563
Traumatic brain injury (TBI) is a complex condition and a leading cause of injury-related disability and death, with significant impacts on patient outcomes. Extracranial organ involvement plays a critical role...
3.
Knopman D, Laskowitz D, Koltai D, Charvet L, Becker J, Federman A, et al.
Trials
. 2024 May;
25(1):326.
PMID: 38755688
Background: Post-acute sequelae of SARS-CoV-2 infection (PASC) symptoms have broad impact, and may affect individuals regardless of COVID-19 severity, socioeconomic status, race, ethnicity, or age. A prominent PASC symptom is...
4.
Kelly-Hedrick M, Liu S, Komisarow J, Hatfield J, Ohnuma T, Treggiari M, et al.
J Intensive Care Med
. 2024 Mar;
39(9):875-882.
PMID: 38449336
Background: There is limited evidence that beta-blockers may provide benefit for patients with moderate-severe traumatic brain injury (TBI) during the acute injury period. Larger studies on utilization patterns and impact...
5.
Kolls B, Muir K, Savitz S, Wechsler L, Pilitsis J, Rahimi S, et al.
Trials
. 2024 Feb;
25(1):150.
PMID: 38419030
Background: Recruitment of participants is the greatest risk to completion of most clinical trials, with 20-40% of trials failing to reach the targeted enrollment. This is particularly true of trials...
6.
Liu S, Kelly-Hedrick M, Komisarow J, Hatfield J, Ohnuma T, Treggiari M, et al.
Anesth Analg
. 2024 Feb;
139(2):366-374.
PMID: 38335145
Background: Traumatic brain injury (TBI) is an expensive and common public health problem. Management of TBI oftentimes includes sedation to facilitate mechanical ventilation (MV) for airway protection. Dexmedetomidine has emerged...
7.
Mace B, Lassiter E, Arulraja E, Chaparro E, Cantillana V, Gupta R, et al.
Neurol Res
. 2024 Jan;
46(4):304-317.
PMID: 38197610
Traumatic brain injury (TBI) from closed-head trauma is a leading cause of disability, with limited effective interventions. Many TBI models impact brain parenchyma directly, and are limited by the fact...
8.
Laskowitz D, Troy J, Poehlein E, Bennett E, Shpall E, Wingard J, et al.
Stem Cells Transl Med
. 2023 Dec;
13(2):125-136.
PMID: 38071749
Stroke remains a leading cause of death and disability in the US, and time-limited reperfusion strategies remain the only approved treatment options. To address this unmet clinical need, we conducted...
9.
Liu S, Kelly-Hedrick M, Temkin N, Barber J, Komisarow J, Hatfield J, et al.
Crit Care Med
. 2023 Nov;
52(4):607-617.
PMID: 37966330
Objective: To examine early sedation patterns, as well as the association of dexmedetomidine exposure, with clinical and functional outcomes among mechanically ventilated patients with moderate-severe traumatic brain injury (msTBI). Design:...
10.
Russell T, Dirar Q, Li Y, Chiang C, Laskowitz D, Yun Y
PLoS One
. 2023 Oct;
18(10):e0288025.
PMID: 37856438
Human induced pluripotent stem cell (hiPSC)-derived brain spheroids can recapitulate the complex cytoarchitecture of the brain, as well as the genetic/epigenetic footprint of human brain development. However, hiPSC-derived 3D models...