Daniel Siebert
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Explore the profile of Daniel Siebert including associated specialties, affiliations and a list of published articles.
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17
Citations
532
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Recent Articles
11.
Schmidt A, Sturm G, Lapp C, Siebert D, Saravia F, Horn H, et al.
Microb Cell Fact
. 2018 Jun;
17(1):90.
PMID: 29898726
Background: A future bioeconomy relies on the development of technologies to convert waste into valuable compounds. We present here an attempt to design a biotechnological cascade for the conversion of...
12.
Baumgart M, Unthan S, Kloss R, Radek A, Polen T, Tenhaef N, et al.
ACS Synth Biol
. 2017 Aug;
7(1):132-144.
PMID: 28803482
Targeted top-down strategies for genome reduction are considered to have a high potential for providing robust basic strains for synthetic biology and industrial biotechnology. Recently, we created a library of...
13.
Siebert D, Wendisch V
Biotechnol Biofuels
. 2015 Jun;
8:91.
PMID: 26110019
Background: Production of the versatile bulk chemical 1,2-propanediol and the potential biofuel 1-propanol is still dependent on petroleum, but some approaches to establish bio-based production from renewable feed stocks and...
14.
Unthan S, Baumgart M, Radek A, Herbst M, Siebert D, Bruhl N, et al.
Biotechnol J
. 2014 Aug;
10(2):290-301.
PMID: 25139579
For synthetic biology applications, a robust structural basis is required, which can be constructed either from scratch or in a top-down approach starting from any existing organism. In this study,...
15.
Beerepoot P, Lam V, Luu A, Tsoi B, Siebert D, Szechtman H
Neurosci Lett
. 2008 Oct;
446(2-3):101-4.
PMID: 18824069
Locomotor sensitization induced by the dopamine agonist quinpirole can be potentiated by co-treatment with the synthetic kappa opioid agonist U69593. The identification of salvinorin A, an active component of the...
16.
Wang Y, Tang K, Inan S, Siebert D, Holzgrabe U, Lee D, et al.
J Pharmacol Exp Ther
. 2004 Sep;
312(1):220-30.
PMID: 15383632
Salvinorin A, TRK-820 (17-cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-[N-methyl-trans-3-(3-furyl) acrylamido]morphinan hydrochloride), and 3FLB (diethyl 2,4-di-[3-fluorophenyl]-3,7-dimethyl-3,7-diazabicyclo[3.3.1]nonane-9-one-1,5-dicarboxylate) are structurally distinctly different from U50,488H [(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide methanesulfonate], the prototypic selective kappa agonist. Here, we investigated their in vitro pharmacological...
17.
Roth B, Baner K, Westkaemper R, Siebert D, Rice K, Steinberg S, et al.
Proc Natl Acad Sci U S A
. 2002 Aug;
99(18):11934-9.
PMID: 12192085
Salvia divinorum, whose main active ingredient is the neoclerodane diterpene Salvinorin A, is a hallucinogenic plant in the mint family that has been used in traditional spiritual practices for its...