Daniel S Gareau
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Explore the profile of Daniel S Gareau including associated specialties, affiliations and a list of published articles.
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20
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322
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Recent Articles
1.
Aguero R, Buchanan K, Navarrete-Dechent C, Marghoob A, Stein J, Landy M, et al.
Cancers (Basel)
. 2024 Sep;
16(17).
PMID: 39272935
Incorporation of dermoscopy and artificial intelligence (AI) is improving healthcare professionals' ability to diagnose melanoma earlier, but these algorithms often suffer from a "black box" issue, where decision-making processes are...
2.
Gareau D, Rochakim N, Choudhury A, Bamkole M, Snuderl M, Zou J, et al.
Front Mol Neurosci
. 2023 Jul;
16:1163447.
PMID: 37465366
Many Alzheimer's disease (AD) patients suffer from altered cerebral blood flow and damaged cerebral vasculature. Cerebrovascular dysfunction could play an important role in this disease. However, the mechanism underlying a...
3.
Combalia M, Garcia S, Malvehy J, Puig S, Guembe Mulberger A, Browning J, et al.
Biomed Opt Express
. 2021 Jul;
12(6):3103-3116.
PMID: 34221648
Standard histopathology is currently the gold standard for assessment of margin status in Mohs surgical removal of skin cancer. Ex vivo confocal microscopy (XVM) is potentially faster, less costly and...
4.
Gareau D, Browning J, Da Rosa J, Suarez-Farinas M, Lish S, Zong A, et al.
J Biomed Opt
. 2020 Nov;
25(11).
PMID: 33247560
Significance: Melanoma is a deadly cancer that physicians struggle to diagnose early because they lack the knowledge to differentiate benign from malignant lesions. Deep machine learning approaches to image analysis...
5.
Browning J, Derr P, Derr K, Doudican N, Michael S, Lish S, et al.
Oncotarget
. 2020 Jul;
11(27):2587-2596.
PMID: 32676161
Cutaneous squamous cell carcinoma (cSCC) causes approximately 10,000 deaths annually in the U. S. Current therapies are largely ineffective against metastatic and locally advanced cSCC. There is a need to...
6.
Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
Kim G, Pacheco D, Saxon D, Yang A, Sabet S, Dutra-Clarke M, et al.
Cell
. 2019 Sep;
179(1):251-267.e24.
PMID: 31539496
In situ transgenesis methods such as viruses and electroporation can rapidly create somatic transgenic mice but lack control over copy number, zygosity, and locus specificity. Here we establish mosaic analysis...
7.
Hosking A, Coakley B, Chang D, Talebi-Liasi F, Lish S, Lee S, et al.
Lasers Surg Med
. 2019 Jan;
51(3):214-222.
PMID: 30653684
Objectives: Early melanoma detection decreases morbidity and mortality. Early detection classically involves dermoscopy to identify suspicious lesions for which biopsy is indicated. Biopsy and histological examination then diagnose benign nevi,...
8.
Gareau D, Krueger J, Hawkes J, Lish S, Dietz M, Guembe Mulberger A, et al.
Biomed Opt Express
. 2017 Sep;
8(8):3807-3815.
PMID: 28856051
For rapid pathological assessment of large surgical tissue excisions with cellular resolution, we present a line scanning, stage scanning confocal microscope (LSSSCM). LSSSCM uses no scanning mirrors. Laser light is...
9.
Gareau D, Da Rosa J, Yagerman S, Carucci J, Gulati N, Hueto F, et al.
Exp Dermatol
. 2016 Oct;
26(7):615-618.
PMID: 27783441
We developed an automated approach for generating quantitative image analysis metrics (imaging biomarkers) that are then analysed with a set of 13 machine learning algorithms to generate an overall risk...
10.
Mu E, M Lewin J, Stevenson M, Meehan S, Carucci J, Gareau D
JAMA Dermatol
. 2016 Sep;
152(12):1335-1341.
PMID: 27603676
Importance: Confocal microscopy has the potential to provide rapid bedside pathologic analysis, but clinical adoption has been limited in part by the need for physician retraining to interpret grayscale images....