Daniel R Faber
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Explore the profile of Daniel R Faber including associated specialties, affiliations and a list of published articles.
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21
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155
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Recent Articles
1.
Michels E, Chouchane O, de Brabander J, de Vos A, Faber D, Douma R, et al.
Front Immunol
. 2024 Nov;
15:1470383.
PMID: 39493755
Introduction: Neutrophils play a dichotomous role in community-acquired pneumonia (CAP), providing protection and potentially causing damage. Existing research on neutrophil function in CAP relies on animal studies, leaving a gap...
2.
Doeleman S, Reijnders T, Joosten S, Schuurman A, van Engelen T, Verhoeff J, et al.
J Infect
. 2024 Mar;
88(4):106131.
PMID: 38431153
Objectives: Lymphopenia at hospital admission occurs in over one-third of patients with community-acquired pneumonia (CAP), yet its clinical relevance and pathophysiological implications remain underexplored. We evaluated outcomes and immune features...
3.
Schuurman A, Chouchane O, Butler J, Peters-Sengers H, Joosten S, Brands X, et al.
JCI Insight
. 2024 Feb;
9(4).
PMID: 38385743
The lipidome of immune cells during infection has remained unexplored, although evidence of the importance of lipids in the context of immunity is mounting. In this study, we performed untargeted...
4.
Reijnders T, Schuurman A, Verhoeff J, van den Braber M, Douma R, Faber D, et al.
Front Immunol
. 2023 Dec;
14:1260283.
PMID: 38077404
Background: Community-acquired pneumonia (CAP) represents a major health burden worldwide. Dysregulation of the immune response plays an important role in adverse outcomes in patients with CAP. Methods: We analyzed peripheral...
5.
Schuurman A, Butler J, Michels E, Otto N, Brands X, Haak B, et al.
iScience
. 2023 Jul;
26(7):107181.
PMID: 37496676
Neutrophils are potent immune cells with key antimicrobial functions. Previous work has shown that neutrophil effector functions are mainly fueled by intracellular glycolysis. Little is known about the state of...
6.
Otto N, Butler J, Schuurman A, Brands X, Haak B, Klarenbeek A, et al.
Biochim Biophys Acta Mol Basis Dis
. 2022 Aug;
1868(11):166519.
PMID: 35964875
Background: Community-acquired pneumonia (CAP) is responsible for a high morbidity and mortality worldwide. Monocytes are essential for pathogen recognition and the initiation of an innate immune response. Immune cells induce...
7.
Kullberg R, Brands X, Klarenbeek A, Butler J, Otto N, Faber D, et al.
iScience
. 2022 Aug;
25(8):104740.
PMID: 35938048
Human studies describing the immunomodulatory role of the intestinal microbiota in systemic infections are lacking. Here, we sought to relate microbiota profiles from 115 patients with community-acquired pneumonia (CAP), both...
8.
Schuurman A, Reijnders T, van Engelen T, Leopold V, de Brabander J, van Linge C, et al.
EBioMedicine
. 2022 Jun;
81:104082.
PMID: 35660785
Background: Community-acquired pneumonia (CAP) can be caused by a variety of pathogens, of which Streptococcus pneumoniae, Influenza and currently SARS-CoV-2 are the most common. We sought to identify shared and...
9.
Brands X, van Engelen T, de Vries F, Haak B, Klarenbeek A, Kanglie M, et al.
J Infect Dis
. 2022 Jan;
225(11):2023-2032.
PMID: 35100411
Background: Strongly elevated ferritin levels have been proposed to reflect systemic hyperinflammation in patients admitted to the intensive care unit. Knowledge of the incidence and pathophysiological implications of hyperferritinemia in...
10.
Kullberg R, Hugenholtz F, Brands X, Kinsella C, Peters-Sengers H, Butler J, et al.
EClinicalMedicine
. 2021 Oct;
39:101074.
PMID: 34611613
Background Bacterial intestinal communities interact with the immune system and may contribute to protection against community-acquired pneumonia (CAP). Intestinal viruses are closely integrated with these bacterial communities, yet the composition...