Daniel R Carrasco
Overview
Explore the profile of Daniel R Carrasco including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
2214
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Recent Articles
1.
Wong K, Maser R, Bachoo R, Menon J, Carrasco D, Gu Y, et al.
Nature
. 2025 Jan;
638(8050):E7.
PMID: 39849018
No abstract available.
2.
Gatt M, Takada K, Mani M, Lerner M, Pick M, Hideshima T, et al.
Br J Haematol
. 2013 May;
162(2):210-20.
PMID: 23647456
Multiple myeloma (MM) is an incurable neoplasm caused by proliferation of malignant plasma cells in the bone marrow (BM). MM is characterized frequently by a complete or partial deletion of...
3.
Sukhdeo K, Paramban R, Vidal J, Elia J, Martin J, Rivera M, et al.
PLoS One
. 2013 Jan;
8(1):e53015.
PMID: 23308131
Colon cancer is a deadly disease affecting millions of people worldwide. Current treatment challenges include management of disease burden as well as improvements in detection and targeting of tumor cells....
4.
Tai Y, Chang B, Kong S, Fulciniti M, Yang G, Calle Y, et al.
Blood
. 2012 Jun;
120(9):1877-87.
PMID: 22689860
Bruton tyrosine kinase (Btk) has a well-defined role in B-cell development, whereas its expression in osteoclasts (OCs) further suggests a role in osteoclastogenesis. Here we investigated effects of PCI-32765, an...
5.
Gatt M, Zhao J, Ebert M, Zhang Y, Chu Z, Mani M, et al.
Blood
. 2010 Oct;
PMID: 20962322
Multiple myeloma is characterized by frequent chromosomal alterations. Deletion of chr 13, especially band 13q14, is commonly observed in early stages of MM, suggesting the presence of tumor suppressor genes...
6.
Hideshima T, Mitsiades C, Ikeda H, Chauhan D, Raje N, Gorgun G, et al.
Blood
. 2010 Mar;
115(18):3772-5.
PMID: 20228272
Constitutive B-cell lymphoma 6 (Bcl-6) expression was undetectable in multiple myeloma (MM) cell lines, except U266 cells. However, it was up-regulated by coculture with bone marrow (BM) stromal cell-culture supernatant...
7.
Mani M, Carrasco D, Zhang Y, Takada K, Gatt M, Dutta-Simmons J, et al.
Cancer Res
. 2009 Sep;
69(19):7577-86.
PMID: 19738061
Several components of the Wnt signaling cascade have been shown to function either as tumor suppressor proteins or as oncogenes in multiple human cancers, underscoring the relevance of this pathway...
8.
Dutta-Simmons J, Zhang Y, Gorgun G, Gatt M, Mani M, Hideshima T, et al.
Blood
. 2009 Aug;
114(13):2699-708.
PMID: 19652203
Multiple myeloma (MM) is a cancer of plasma cells with complex molecular characteristics that evolves from monoclonal gammopathy of undetermined significance, a highly prevalent premalignant condition. MM is the second...
9.
Jinushi M, Nakazaki Y, Carrasco D, Draganov D, Souders N, Johnson M, et al.
Cancer Res
. 2008 Nov;
68(21):8889-98.
PMID: 18974133
The pathogenesis of malignant melanoma involves the interplay of tumor cells with normal host elements, but the underlying mechanisms are incompletely understood. Here, we show that milk fat globule EGF-8...
10.
Leleu X, Eeckhoute J, Jia X, Roccaro A, Moreau A, Farag M, et al.
Blood
. 2008 Mar;
111(10):5068-77.
PMID: 18334673
The nuclear factor-kappaB (NF-kappaB) path-way has been implicated in tumor B-cell survival, growth, and resistance to therapy. Because tumor cells overcome single-agent antitumor activity, we hypothesized that combination of agents...