Daniel OToole
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Explore the profile of Daniel OToole including associated specialties, affiliations and a list of published articles.
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53
Citations
1033
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Recent Articles
11.
McCarthy S, Rohde C, Angel M, Masterson C, MacLoughlin R, Fandino J, et al.
Nucleic Acid Ther
. 2023 Feb;
33(2):148-158.
PMID: 36811461
Acute respiratory distress syndrome (ARDS), a rapid onset inflammatory lung disease with no effective specific therapy, typically has pathogenic etiology termed pneumonia. In previous studies nuclear factor-κB (NF-κB) inhibitor α...
12.
Alagesan S, Brady J, Byrnes D, Fandino J, Masterson C, McCarthy S, et al.
Stem Cell Res Ther
. 2022 Feb;
13(1):75.
PMID: 35189962
Cell therapy, particularly mesenchymal stem/stromal (MSC) therapy, has been investigated for a wide variety of disease indications, particularly those with inflammatory pathologies. However, recently it has become evident that the...
13.
Horie S, Gonzalez H, Brady J, Devaney J, Scully M, OToole D, et al.
Int J Mol Sci
. 2021 Dec;
22(23).
PMID: 34884645
Background: Ventilator-induced lung injury (VILI) frequently worsens acute respiratory distress syndrome (ARDS) severity. Human mesenchymal stem/stromal cells (MSCs) offer considerable therapeutic promise, but the key impediments of clinical translation stem...
14.
Masterson C, OToole D, Laffey J
Am J Respir Crit Care Med
. 2021 Aug;
204(8):878-879.
PMID: 34375575
No abstract available.
15.
Hosey-Cojocari C, Chan S, Friesen C, Robinson A, Williams V, Swanson E, et al.
Clin Transl Sci
. 2021 May;
14(5):2008-2016.
PMID: 33982422
The liver is the primary organ responsible for clearing most drugs from the body and thus determines systemic drug concentrations over time. Drug clearance by the liver appears to be...
16.
McDonnell M, Hunt E, Ward C, Pearson J, OToole D, Laffey J, et al.
ERJ Open Res
. 2021 Mar;
6(4).
PMID: 33693049
The inter-relationship between chronic respiratory disease and reflux disease in the airway reflux paradigm is extremely complex and remains poorly characterised. Reflux disease is reported to cause or contribute to...
17.
Masterson C, Horie S, McCarthy S, Gonzalez H, Byrnes D, Brady J, et al.
Interface Focus
. 2021 Feb;
11(2):20200032.
PMID: 33628425
Carbon dioxide (CO) has long been considered, at best, a waste by-product of metabolism, and at worst, a toxic molecule with serious health consequences if physiological concentration is dysregulated. However,...
18.
Gonzalez H, Keane C, Masterson C, Horie S, Elliman S, Higgins B, et al.
Int J Mol Sci
. 2020 Nov;
21(21).
PMID: 33158246
Mesenchymal stromal cells (MSCs) have a multimodal, immunomodulatory mechanism of action and are now in clinical trials for single organ and systemic sepsis. However, a number of practicalities around source,...
19.
Spaedy A, OToole D, Aylward C
Mo Med
. 2020 Aug;
117(4):380-382.
PMID: 32848277
This manuscript aims to outline the pertinent epidemiology, presentation, diagnosis, and treatment of patients who present with breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) as it pertains to primary care,...
20.
Masterson C, McCarthy S, OToole D, Laffey J
Expert Opin Drug Deliv
. 2020 Aug;
17(12):1689-1702.
PMID: 32842784
Introduction: Cell-based delivery systems offer considerable promise as novel and innovative therapeutics to target the respiratory system. These systems consist of cells and/or their extracellular vesicles that deliver their contents,...